# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4779405 | EUB0000285b | Kd | > | 10 | uM | ALA5214789 | nM | Homo sapiens | |||
2. | ALA4779405 | EUB0000285b | % of control | = | 0 | % | ALA5214788 | % | Homo sapiens | |||
3. | Lorlatinib | 8k, PF-06463922 | Ki | = | 2.7 | nM | ALA5213165 | 8.57 | nM | Homo sapiens | ||
4. | MPS1-IN-1 | Mps1-IN-1 | IC50 | = | 29 | nM | ALA5212778 | 7.54 | nM | Homo sapiens | ||
5. | MPS1-IN-1 | Mps1-IN-1 | % of control | = | 1.2 | % | ALA5212777 | % | Homo sapiens | |||
6. | BAY-885 | BAY-885; 41 | % of control | = | 49 | % | ALA5213232 | % | Homo sapiens | |||
7. | ALA5201248 | 38 | INH | = | 35 | % | ALA5157151 | % | Homo sapiens | |||
8. | ALA5187271 | 29 | INH | = | 44 | % | ALA5157151 | % | Homo sapiens | |||
9. | Gilteritinib | GILTERITINIB | IC50 | = | 0.35 | nM | ALA5150862 | 9.46 | nM | Homo sapiens | ||
10. | Gilteritinib | GILTERITINIB | IC5 | = | 0.35 | nM | ALA5150836 | nM | Homo sapiens | |||
11. | BMS-777607 | 10, BMS-777607 | INH | = | 79.9 | % | ALA4432483 | % | Homo sapiens | |||
12. | ALA4582423 | 1a | INH | = | 84.1 | % | ALA4432483 | % | Homo sapiens | |||
13. | ALA4445335 | Roxyl-ZV-5J | INH | = | 0 | % | ALA4407997 | % | Homo sapiens | |||
14. | ALA4455923 | 48c | INH | < | 50 | % | ALA4405606 | % | Homo sapiens | |||
15. | ALA4559936 | (+/-)-6 | Activity | = | 100 | % | ALA4391413 | % | Homo sapiens | |||
16. | ALA4564973 | 50 | INH | = | 100 | % | ALA4389787 | % | Homo sapiens | |||
17. | ALA4555459 | 43 | INH | = | 100 | % | ALA4389310 | % | Homo sapiens | |||
18. | ALA4545456 | 24 | INH | = | 25.5 | % | ALA4387280 | % | Homo sapiens | |||
19. | Abemaciclib | ABEMACICLIB | INH | = | 10.5 | % | ALA4387280 | % | Homo sapiens | |||
20. | ALA4473365 | 7c | IC50 | = | 4 | nM | ALA4382835 | 8.40 | nM | Homo sapiens |