| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2048326 | 2k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 2. |  ALA2048327 | 3k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 3. |  ALA2048328 | 4k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 4. |  ALA2048329 | 5k, mixture of E and Z isomers | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 5. |  ALA2048330 | 6k, mixture of diastereomers | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 6. |  ALA2048331 | 7k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 7. |  ALA2048332 | 8k, mixture of diastereomers | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 8. |  ALA2048333 | 9k, mixture of diastereomers | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 9. |  ALA2048334 | 10k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 10. |  ALA2048335 | 11k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 11. |  ALA69851 | 13 | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 12. |  ALA2048336 | 13k | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 13. |  4-cholesten-3-one | 1 | Activity | 0 | ALA2051057 | Active | Mycobacterium tuberculosis | |||||
| 14. |  ALA2048319 | 5, 26-Methylcholesta-5,25(26)-dienol, E/Z mixture | Kd(app) | = | 0.45 | uM | ALA2050039 | 6.35 | nM | Mycobacterium tuberculosis | ||
| 15. |  ALA2048318 | 4, Cholesta-5,25-dienol | Kd(app) | = | 0.25 | uM | ALA2050039 | 6.60 | nM | Mycobacterium tuberculosis | ||
| 16. |  ALA2048321 | 7, 27-Norcholesta-5,25-dienol | INH | 0 | ALA2051060 | Not Active | % | Mycobacterium tuberculosis | ||||
| 17. |  Lanosterol | 5 | Activity | = | 37 | % | ALA2050050 | % | Mycobacterium tuberculosis | |||
| 18. |  Coprostanol | 12 | Activity | = | 50.9 | % | ALA2050050 | % | Mycobacterium tuberculosis | |||
| 19. |  3β-hydroxy-5,24-cholestadiene | 1, desmosterol | Activity | = | 47.5 | % | ALA2050050 | % | Mycobacterium tuberculosis | |||
| 20. |  ALA2048323 | 9, 25-Bromo-27-norcholesterol, mixture of diastereomers | Activity | = | 65.1 | % | ALA2050050 | % | Mycobacterium tuberculosis |
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