# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | AZD5718 | 12; AZD5718 | IC50 | > | 33 | uM | ALA4393836 | nM | Homo sapiens | |||
2. | ALA4474619 | 11 | IC50 | > | 33 | uM | ALA4393836 | nM | Homo sapiens | |||
3. | ALA4563459 | 10 | IC50 | > | 33 | uM | ALA4393836 | nM | Homo sapiens | |||
4. | ALA2152523 | 2 | IC50 | = | 1.4 | uM | ALA4392944 | 5.85 | nM | Homo sapiens | ||
5. | ALA4438854 | 2 | IC50 | = | 17 | uM | ALA4392944 | 4.77 | nM | Homo sapiens | ||
6. | ALA4476275 | 3 | IC50 | > | 33 | uM | ALA4392944 | nM | Homo sapiens | |||
7. | ALA4437013 | 4 | IC50 | = | 60 | uM | ALA4392944 | 4.22 | nM | Homo sapiens | ||
8. | ALA4475999 | 10; AZ13395438 | IC50 | > | 33 | uM | ALA4392944 | nM | Homo sapiens | |||
9. | AZD9898 | BDBM223287 | INH | 0 | ALA4378226 | Not Active | % | Homo sapiens | ||||
10. | ALA4528928 | 4i | INH | 0 | ALA4351288 | Not Active | % | Homo sapiens | ||||
11. | ALA4282052 | 10 | IC50 | > | 15 | uM | ALA4270254 | nM | Homo sapiens | |||
12. | ALA3358006 | 16 | IC50 | = | 27 | uM | ALA3384646 | 4.57 | nM | Homo sapiens | ||
13. | ALA3314349 | 1 | IC50 | = | 10.5 | uM | ALA3368360 | 4.98 | nM | Homo sapiens | ||
14. | ALA3314352 | 9c | IC50 | > | 33 | uM | ALA3368360 | nM | Homo sapiens | |||
15. | ALA3314362 | 25e | IC50 | > | 33 | uM | ALA3368360 | nM | Homo sapiens | |||
16. | ALA4064608 | 28 | IC50 | > | 30 | uM | ALA4027001 | nM | Homo sapiens | |||
17. | ALA1835153 | 65 | IC50 | > | 10 | uM | ALA1840134 | nM | Homo sapiens | |||
18. | ALA1773877 | 6 | IC50 | > | 10000 | nM | ALA1775459 | nM | Homo sapiens | |||
19. | ALA1774043 | 5 | IC50 | > | 9000 | nM | ALA1775459 | nM | Homo sapiens | |||
20. | 2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(6S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-3-yl]acetamide | 6, MK-8825 | IC50 | > | 20000 | nM | ALA2040048 | nM | Homo sapiens |