# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA504763 | 7 | IC50 | = | 19 | uM | ALA4229712 | 4.72 | nM | Homo sapiens | ||
2. | ALA4244153 | 25 | IC50 | = | 250 | nM | ALA4229712 | 6.60 | nM | Homo sapiens | ||
3. | ALA3927308 | BDBM251882 | IC50 | = | 30 | nM | ALA4229713 | 7.52 | nM | Homo sapiens | ||
4. | ALA4247942 | 27 | IC50 | = | 23 | nM | ALA4229713 | 7.64 | nM | Homo sapiens | ||
5. | ALA4114217 | BDBM251408 | IC50 | = | 1 | nM | ALA4229714 | 9.00 | nM | Homo sapiens | ||
6. | Iptacopan | IPTACOPAN | IC50 | = | 0.4 | uM | ALA4614788 | 6.40 | nM | Homo sapiens | ||
7. | Iptacopan | IPTACOPAN | IC50 | = | 0.13 | uM | ALA4614753 | 6.89 | nM | Homo sapiens | ||
8. | ALA4639592 | 40 | IC50 | = | 0.14 | uM | ALA4614753 | 6.85 | nM | Homo sapiens | ||
9. | ALA4644208 | 39 | IC50 | = | 0.11 | uM | ALA4614753 | 6.96 | nM | Homo sapiens | ||
10. | ALA4632794 | 38 | IC50 | = | 0.18 | uM | ALA4614753 | 6.75 | nM | Homo sapiens | ||
11. | ALA4641109 | 37 | IC50 | = | 0.24 | uM | ALA4614753 | 6.62 | nM | Homo sapiens | ||
12. | ALA4646504 | 36 | IC50 | = | 0.15 | uM | ALA4614753 | 6.82 | nM | Homo sapiens | ||
13. | ALA4644994 | (+/-)-35 | IC50 | = | 0.25 | uM | ALA4614753 | 6.60 | nM | Homo sapiens | ||
14. | Iptacopan | IPTACOPAN | IC50 | = | 0.012 | uM | ALA4614752 | 7.92 | nM | Homo sapiens | ||
15. | ALA4639592 | 40 | IC50 | = | 0.006 | uM | ALA4614752 | 8.22 | nM | Homo sapiens | ||
16. | ALA4644208 | 39 | IC50 | = | 0.018 | uM | ALA4614752 | 7.75 | nM | Homo sapiens | ||
17. | ALA4632794 | 38 | IC50 | = | 0.018 | uM | ALA4614752 | 7.75 | nM | Homo sapiens | ||
18. | ALA4641109 | 37 | IC50 | = | 0.018 | uM | ALA4614752 | 7.75 | nM | Homo sapiens | ||
19. | ALA4646504 | 36 | IC50 | = | 0.024 | uM | ALA4614752 | 7.62 | nM | Homo sapiens | ||
20. | ALA4644994 | (+/-)-35 | IC50 | = | 0.033 | uM | ALA4614752 | 7.48 | nM | Homo sapiens |