# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4468555 | (+)-5d; compound A | INH | 0 | ALA4427800 | Dose-dependent effect | % | Homo sapiens | ||||
2. | ALA4468555 | (+)-5d; compound A | EC50 | = | 39 | nM | ALA4427800 | 7.41 | nM | Homo sapiens | ||
3. | ALA4515745 | (+/-)-5a | INH | 0 | ALA4427800 | Dose-dependent effect | % | Homo sapiens | ||||
4. | ALA4515745 | (+/-)-5a | EC50 | = | 79 | nM | ALA4427800 | 7.10 | nM | Homo sapiens | ||
5. | ALA4468555 | (+)-5d; compound A | IC50 | = | 2.2 | nM | ALA4427798 | 8.66 | nM | Homo sapiens | ||
6. | ALA4470356 | (+)-5c | IC50 | = | 1.5 | nM | ALA4427798 | 8.82 | nM | Homo sapiens | ||
7. | ALA4549646 | (+)-5b | IC50 | = | 1.7 | nM | ALA4427798 | 8.77 | nM | Homo sapiens | ||
8. | ALA4579540 | (+)-5a | IC50 | = | 1.6 | nM | ALA4427798 | 8.80 | nM | Homo sapiens | ||
9. | ALA4515745 | (+/-)-5a | IC50 | = | 2.7 | nM | ALA4427798 | 8.57 | nM | Homo sapiens | ||
10. | ALA4579162 | (+/-)-4 | IC50 | = | 14 | nM | ALA4427798 | 7.85 | nM | Homo sapiens | ||
11. | ALA4466617 | (+/-)-3 | IC50 | = | 19 | nM | ALA4427798 | 7.72 | nM | Homo sapiens | ||
12. | ALA4483703 | (+/-)-2 | IC50 | = | 24 | nM | ALA4427798 | 7.62 | nM | Homo sapiens | ||
13. | ALA3633366 | 5b | INH | 0 | ALA3636402 | Not Active | % | Homo sapiens | ||||
14. | ALA3633365 | 5a | INH | 0 | ALA3636402 | Not Active | % | Homo sapiens | ||||
15. | Physodic acid | 4, NSC-685589 | Imax | = | 60 | % | ALA3860201 | % | Homo sapiens | |||
16. | Physodic acid | 4, NSC-685589 | IC50 | = | 91.4 | uM | ALA3860201 | 4.04 | nM | Homo sapiens | ||
17. | Physodic acid | 4, NSC-685589 | Imax | = | 70 | % | ALA3860188 | % | Homo sapiens | |||
18. | Physodic acid | 4, NSC-685589 | IC50 | = | 29.6 | uM | ALA3860188 | 4.53 | nM | Homo sapiens | ||
19. | (S)-ARN2508 | (+)-10r | Activity | = | -3.3 | % | ALA3777465 | % | Homo sapiens | |||
20. | Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate | 2 | INH | > | 30 | % | ALA3755564 | % | Homo sapiens |