| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Trichloroethylene | Trichloroethene | mechanism based inhibition | 0 | ALA1908271 | Cytochrome P450 mechanistic inhibitor: PMID 9851676 | Rattus norvegicus | |||||
| 2. |  tert-Butyl isothiocyanate | tert-Butyl isothiocyanate (tBITC) | mechanism based inhibition | 0 | ALA1908271 | Cytochrome P450 mechanistic inhibitor: PMID 9778311 | Rattus norvegicus | |||||
| 3. | tert-Butyl isothiocyanate | tert-Butyl isothiocyanate (tBITC) | mechanism based inhibition | 0 | ALA1908252 | Cytochrome P450 mechanistic inhibitor: PMID 9778311 | Rattus norvegicus | |||||
| 4. |  ALA1908234 | 1,2-Dichloroethylene | mechanism based inhibition | 0 | ALA1908271 | Cytochrome P450 mechanistic inhibitor: PMID 9851676 | Rattus norvegicus | |||||
| 5. |  ALA1908233 | Diallylsulfone | mechanism based inhibition | 0 | ALA1908271 | Cytochrome P450 mechanistic inhibitor: PMID 9084912 | Rattus norvegicus | |||||
| 6. | ALA1908233 | Diallylsulfone | kinact | = | 0.32 | min-1 | ALA1908272 | Cytochrome P450 mechanistic inhibitor: PMID 1807447 | min-1 | Rattus norvegicus | ||
| 7. | ALA1908233 | Diallylsulfone | ki | = | 188 | uM | ALA1908272 | Cytochrome P450 mechanistic inhibitor: PMID 1807447 | nM | Rattus norvegicus | ||
| 8. |  ALA1908229 | tert-Butyl 1-methyl-2-propynyl Ether | kinact | = | 0.12 | min-1 | ALA1908251 | Cytochrome P450 mechanistic inhibitor: PMID 12482238 | min-1 | Rattus norvegicus | ||
| 9. | ALA1908229 | tert-Butyl 1-methyl-2-propynyl Ether | ki | = | 100 | uM | ALA1908251 | 4.00 | Cytochrome P450 mechanistic inhibitor: PMID 12482238 | nM | Rattus norvegicus | |
| 10. |  3,3-Dimethyl-1-butyne | tert-Butyl Acetylene (tBA) | kinact | = | 0.2 | min-1 | ALA1908251 | Cytochrome P450 mechanistic inhibitor: PMID 12482238 | min-1 | Rattus norvegicus | ||
| 11. | 3,3-Dimethyl-1-butyne | tert-Butyl Acetylene (tBA) | ki | = | 1000 | uM | ALA1908251 | Cytochrome P450 mechanistic inhibitor: PMID 12482238 | nM | Rattus norvegicus | ||
| 12. |  ALA3526190 | DB868 | Drug metabolism | 0 | ALA3536452 | metabolite_not_detected | Rattus norvegicus | |||||
| 13. | ALA3526190 | DB868 | Drug metabolism | 0 | ALA3536079 | metabolite_not_detected | Rattus norvegicus | |||||
| 14. |  ALA3781527 | 3; 3FDT | Drug metabolism | 0 | ALA3782859 | metabolite_detected | Rattus norvegicus | |||||
| 15. | ALA3781527 | 3; 3FDT | Drug metabolism | 0 | ALA3784372 | metabolite_detected | Rattus norvegicus | |||||
| 16. | ALA3781527 | 3; 3FDT | Drug metabolism | 0 | ALA3784250 | metabolite_notdetected | Rattus norvegicus | |||||
| 17. |  ALA5182450 | GZ | Ki | = | 195.7 | uM | ALA5118025 | nM | Rattus norvegicus | |||
| 18. |  ALA464300 | QC-47 | IC50 | = | 3.6 | uM | ALA1015214 | 5.44 | nM | Rattus norvegicus | ||
| 19. |  ALA447959 | QC-40 | IC50 | > | 100 | uM | ALA1015214 | nM | Rattus norvegicus | |||
| 20. |  ALA474379 | 29 | IC50 | > | 100 | uM | ALA1015214 | nM | Rattus norvegicus |
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