Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	(4aR,7aS)-2-amino-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-4-one	BDBM9488	INH		0		ALA3801561		Not Active	%	Homo sapiens
2.	ALA3794064	3; BMS-520	IC50	>	40	uM	ALA3803543			nM	Homo sapiens
3.	ALA3686863	BDBM142234	IC50	>	10	uM	ALA3795705			nM	Homo sapiens
4.	ALA3686863	BDBM142234	INH		0		ALA3795738		Not Active	%	Homo sapiens
5.	ALA3794145	5b	IC50	>	40	uM	ALA3795105			nM	Homo sapiens
6.	ALA3578244	44	INH		0		ALA3796225		Not Active	%	Homo sapiens
7.	ALA3786572	59	INH		0		ALA3791500		Not Active	%	Homo sapiens
8.	ALA3785323	10; MK-8831	INH		0		ALA3788817		Not Active	%	Homo sapiens
9.	ALA3781527	3; 3FDT	Drug metabolism		0		ALA3784246		metabolite_notdetected		Homo sapiens
10.	ALA3771118	4a; PF-06761281	INH		0		ALA3773468		Not Active	%	Homo sapiens
11.	vibegron	VIBEGRON	IC50	>	100	uM	ALA3766306			nM	Homo sapiens
12.	MAP4K4-IN-3	17	INH	<	15	%	ALA3755439			%	Homo sapiens
13.	PF-6260933	16; PF-6260933	INH	<	15	%	ALA3755439			%	Homo sapiens
14.	3-[[6-[3-(hydroxymethyl)phenyl]-3-methylpyridine-2-carbonyl]amino]-2,4-dimethylbenzoic acid	7a	IC50	>	10	uM	ALA3754938			nM	Homo sapiens
15.	ALA3740325	7e	IC50	>	10	uM	ALA3744269			nM	Homo sapiens
16.	HTL6641	27; HTL6641	pIC50	<	5		ALA3742905			nM	Homo sapiens
17.	ALA3736156	3	pIC50	<	5		ALA3738822			nM	Homo sapiens
18.	ALA3736433	2	pIC50	<	5		ALA3738822			nM	Homo sapiens
19.	propranolol	16	pIC50	<	5		ALA3738822			nM	Homo sapiens
20.	ALA3672842	BDBM155255	IC50	=	47430	nM	ALA3707818	4.32	297634	nM	Homo sapiens