Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA361184	5	Ratio	=	0.85		ALA2444336			Mus musculus
2.	ALA2440363	(S)-7	EC50	=	0.9	nM	ALA2444337	9.05	nM	Mus musculus
3.	ALA180886	3	Ratio	=	1.1		ALA2444336			Mus musculus
4.	(S)-N-[1-(3-morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide	(S)-1	Ratio	=	1.4		ALA2444336			Mus musculus
5.	Retigabine	1 (Retigabine)	Ratio	=	1.6		ALA2444336			Mus musculus
6.	ALA176931	(S)-2	Ratio	=	1.8		ALA2444336			Mus musculus
7.	ALA401942	table 1, R5C1	Ratio	=	2.2		ALA2444336			Mus musculus
8.	ALA401942	table 1, R5C1	EC50	=	2.4	nM	ALA2444337	8.62	nM	Mus musculus
9.	ALA2440363	(S)-7	Ratio	=	2.9		ALA2444336			Mus musculus
10.	ALA361184	5	EC50	=	10	nM	ALA2444337	8.00	nM	Mus musculus
11.	ALA180886	3	EC50	=	20	nM	ALA2444337	7.70	nM	Mus musculus
12.	ALA401942	table 1, R5C1	Efficacy	=	38	%	ALA2444335		%	Mus musculus
13.	ALA176931	(S)-2	EC50	=	60	nM	ALA2444337	7.22	nM	Mus musculus
14.	Retigabine	1 (Retigabine)	EC50	=	1300	nM	ALA2444337	5.89	nM	Mus musculus
15.	(S)-N-[1-(3-morpholin-4-yl-phenyl)-ethyl]-3-phenyl-acrylamide	(S)-1	EC50	=	3200	nM	ALA2444337	5.50	nM	Mus musculus
16.	ALA2440362	(R)-6	EC50	>	10000	nM	ALA2444337		nM	Mus musculus
17.	ALA2440364	(R)-7	EC50	>	10000	nM	ALA2444337		nM	Mus musculus
18.	Retigabine	1 (Retigabine)	E/Eref	=	1.6		ALA836871			Mus musculus
19.	Retigabine	1 (Retigabine)	EC50	=	1.3	uM	ALA838011	5.89	nM	Mus musculus
20.	ALA183545	10	E/Eref	=	1.9		ALA836871			Mus musculus