# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2413155 | [18F]2, [18F]FECUMI-101 | Drug metabolism | 0 | ALA2416503 | Active | Papio anubis | |||||
2. | Auglurant | 1 | Occ50 | = | 0.06 | mg kg-1 | ALA4039308 | mg kg-1 | Papio anubis | |||
3. | Auglurant | 1 | Cp(f) | = | 6.7 | nM | ALA4039307 | nM | Papio anubis | |||
4. | Auglurant | 1 | Cp | = | 56 | nM | ALA4039306 | nM | Papio anubis | |||
5. | Auglurant | 1 | Occ | = | 89 | % | ALA4039305 | % | Papio anubis | |||
6. | Buspirone hydrochloride | Buspirone hydrochloride | Occ | = | 80 | % | ALA3591365 | % | Papio anubis | |||
7. | Buspirone hydrochloride | Buspirone hydrochloride | Occ | < | 20 | % | ALA3591364 | % | Papio anubis | |||
8. | ALA3526550 | [18F]-M7 | Cp | = | 50 | % | ALA3532373 | % | Papio anubis | |||
9. | ALA451770 | [F18]-15 | t1/2 | = | 19 | min | ALA3535312 | hr | Papio anubis | |||
10. | ALA451770 | [F18]-15 | t1/2 | = | 12 | min | ALA3535311 | hr | Papio anubis | |||
11. | ALA451770 | [F18]-15 | Drug recovery | = | 94 | % | ALA3535309 | % | Papio anubis | |||
12. | ALA451770 | [F18]-15 | Stability | = | 11 | % | ALA3535316 | % | Papio anubis | |||
13. | ALA451770 | [F18]-15 | Stability | = | 46 | % | ALA3535315 | % | Papio anubis | |||
14. | ALA1215851 | 1h | Activity | 0 | ALA1219613 | Non-toxic | Papio anubis | |||||
15. | ALA1215851 | 1h | Activity | 0 | ALA1219612 | Active | Papio anubis | |||||
16. | ALA1215851 | 1h | Activity | 0 | ALA1219611 | Active | Papio anubis | |||||
17. | ALA447432 | [18F](-)-6a | t1/2 | 0 | ALA990854 | Not Determined | Papio anubis | |||||
18. | ALA515005 | [18F](-)-6b | t1/2 | = | 210 | min | ALA990854 | hr | Papio anubis | |||
19. | ALA478020 | [18F](-)-6c | t1/2 | = | 80 | min | ALA990854 | hr | Papio anubis | |||
20. | ALA515332 | [18F](-)-3 | t1/2 | 0 | ALA990854 | Not Determined | Papio anubis |