# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2368118 | Deoxoartelinic acid | Activity | = | 98.7 | % | ALA5246810 | % | Plasmodium chabaudi | |||
2. | ALA5289561 | Arteether | Survival | = | 60 | % | ALA5241727 | % | Plasmodium chabaudi | |||
3. | ALA5283720 | 14c | Survival | = | 100 | % | ALA5241727 | % | Plasmodium chabaudi | |||
4. | ALA4447679 | 11 | ED50 | = | 1.4 | mg kg-1 | ALA4400868 | mg.kg-1 | Plasmodium chabaudi | |||
5. | ALA4436020 | 54b; CWHM-1008 | ED99 | = | 30 | mg/kg/day | ALA4392059 | mg/kg/day | Plasmodium chabaudi | |||
6. | ALA4436020 | 54b; CWHM-1008 | ED90 | = | 20 | mg/kg/day | ALA4392059 | mg/kg/day | Plasmodium chabaudi | |||
7. | ALA4436020 | 54b; CWHM-1008 | INH | = | 98.7 | % | ALA4392049 | % | Plasmodium chabaudi | |||
8. | Chloroquine | Chloroquine | INH | = | 95 | % | ALA4392048 | % | Plasmodium chabaudi | |||
9. | ALA4436020 | 54b; CWHM-1008 | INH | = | 75.2 | % | ALA4392048 | % | Plasmodium chabaudi | |||
10. | ALA4436020 | 54b; CWHM-1008 | INH | = | 22.4 | % | ALA4392047 | % | Plasmodium chabaudi | |||
11. | ALA4759278 | (-)-32a; CWHM-1552 | INH | = | 34 | % | ALA4667956 | % | Plasmodium chabaudi | |||
12. | ALA4759278 | (-)-32a; CWHM-1552 | INH | = | 94.1 | % | ALA4667955 | % | Plasmodium chabaudi | |||
13. | ALA4755729 | (-)-31a | INH | = | 65.3 | % | ALA4667955 | % | Plasmodium chabaudi | |||
14. | ALA4750688 | (-)-30a | INH | = | 61.2 | % | ALA4667955 | % | Plasmodium chabaudi | |||
15. | Chloroquine | Chloroquine | INH | = | 99.9 | % | ALA4667955 | % | Plasmodium chabaudi | |||
16. | ALA4436020 | 54b; CWHM-1008 | INH | = | 92.2 | % | ALA4667937 | % | Plasmodium chabaudi | |||
17. | ALA4759278 | (-)-32a; CWHM-1552 | INH | = | 99.9 | % | ALA4667937 | % | Plasmodium chabaudi | |||
18. | ALA4759278 | (-)-32a; CWHM-1552 | ED99 | = | 30 | mg/kg/day | ALA4667927 | mg/kg/day | Plasmodium chabaudi | |||
19. | ALA4759278 | (-)-32a; CWHM-1552 | ED90 | < | 10 | mg/kg/day | ALA4667927 | mg/kg/day | Plasmodium chabaudi | |||
20. | ALA3326639 | 11aA | INH | 0 | ALA3372600 | Active | % | Plasmodium chabaudi |