# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Artesunate | 1d (Artesunate) | IC50 | = | 0.003 | uM | ALA4481289 | 8.48 | nM | Plasmodium vivax | ||
2. | mefloquine | 3, mefloquine-(11S,2'R) | IC50 | = | 0.044 | uM | ALA4481289 | 7.36 | nM | Plasmodium vivax | ||
3. | ALA303933 | PQ(Piperaquine) | IC50 | = | 0.045 | uM | ALA4481289 | 7.34 | nM | Plasmodium vivax | ||
4. | Chloroquine | Chloroquine | IC50 | = | 0.048 | uM | ALA4481289 | 7.32 | nM | Plasmodium vivax | ||
5. | ALA1255726 | 15 | IC50 | = | 0.016 | uM | ALA4481289 | 7.80 | nM | Plasmodium vivax | ||
6. | ALA4876457 | 98; DSM846 | EC50 | = | 0.044 | uM | ALA4812781 | 7.36 | nM | Plasmodium vivax | ||
7. | ALA4848632 | 79; DSM705 | EC50 | = | 0.12 | uM | ALA4812781 | 6.92 | nM | Plasmodium vivax | ||
8. | 4,4'-Diaminodiphenyl Sulfone | 1 | IC50 | = | 1625 | nM | ALA4683342 | 5.79 | nM | Plasmodium vivax | ||
9. | Sulfadoxin | sulfadoxine | IC50 | = | 10 | ng/ml | ALA4683341 | ug.mL-1 | Plasmodium vivax | |||
10. | ALA4071177 | NITD609 | IC50 | < | 10 | nM | ALA4012325 | nM | Plasmodium vivax | |||
11. | Pafuramidine | 3 | Activity | > | 95 | % | ALA3993258 | % | Plasmodium vivax | |||
12. | DSM265 | 38, DSM265 | EC50 | = | 529 | nM | ALA4378134 | 6.28 | nM | Plasmodium vivax | ||
13. | DSM265 | 38, DSM265 | EC50 | = | 190 | nM | ALA4378133 | 6.72 | nM | Plasmodium vivax | ||
14. | DSM265 | 38, DSM265 | Ratio | = | 0.77 | ALA4378131 | Plasmodium vivax | |||||
15. | ganaplacide | 22 | Time | = | 24 | hr | ALA4378099 | hr | Plasmodium vivax | |||
16. | ganaplacide | 22 | Time | = | 24 | hr | ALA4378098 | hr | Plasmodium vivax | |||
17. | ganaplacide | 22 | EC50 | = | 5.5 | nM | ALA4378075 | 8.26 | nM | Plasmodium vivax | ||
18. | NITD-609 | 19a | Time | = | 30 | hr | ALA4378074 | hr | Plasmodium vivax | |||
19. | NITD-609 | 19a | Time | = | 12 | hr | ALA4378072 | hr | Plasmodium vivax | |||
20. | NITD-609 | 19a | Activity | = | 100 | % | ALA4378066 | % | Plasmodium vivax |