# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ML300 | 16e, ML300, SID 99289112 | CLH | = | 67 | ml/min.kg | ALA2445673 | mL.min-1.kg-1 | Rattus norvegicus | |||
2. | ML188 | 16-(R), SID99350510 | CLH | = | 69 | ml/min.kg | ALA2445673 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA2441085 | 4 | IC50 | = | 290 | nM | ALA2446441 | 6.54 | nM | Rattus norvegicus | ||
4. | ALA2441086 | 5 | IC50 | = | 91 | nM | ALA2446441 | 7.04 | nM | Rattus norvegicus | ||
5. | ALA2441087 | 6 | IC50 | = | 77 | nM | ALA2446441 | 7.11 | nM | Rattus norvegicus | ||
6. | ALA2441088 | 7 | IC50 | = | 130 | nM | ALA2446441 | 6.89 | nM | Rattus norvegicus | ||
7. | ALA2441089 | 19 | IC50 | = | 38 | nM | ALA2446441 | 7.42 | nM | Rattus norvegicus | ||
8. | ALA2440128 | 20 | IC50 | = | 28 | nM | ALA2446441 | 7.55 | nM | Rattus norvegicus | ||
9. | ALA2441090 | 21 | IC50 | = | 18 | nM | ALA2446441 | 7.75 | nM | Rattus norvegicus | ||
10. | ALA2441083 | 22 | IC50 | = | 46 | nM | ALA2446441 | 7.34 | nM | Rattus norvegicus | ||
11. | ALA2441084 | 23, DF-461 | IC50 | = | 19 | nM | ALA2446441 | 7.72 | nM | Rattus norvegicus | ||
12. | ALA2431760 | 19 | CLH | = | 38 | ml/min.kg | ALA2434423 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA2431765 | 27 | CLH | 0 | ALA2434423 | Not Determined | Rattus norvegicus | |||||
14. | ALA2431766 | 33 | CLH | = | 21 | ml/min.kg | ALA2434423 | mL.min-1.kg-1 | Rattus norvegicus | |||
15. | ALA2431766 | 33 | Drug metabolism | 0 | ALA2434318 | Active | Rattus norvegicus | |||||
16. | ALA2431766 | 33 | Drug metabolism | 0 | ALA2434316 | Active | Rattus norvegicus | |||||
17. | ALA2431466 | 14 | CLH | = | 29 | uL/min | ALA2434085 | uL/min | Rattus norvegicus | |||
18. | ALA2431362 | 16 | CLH | = | 20 | uL/min | ALA2434085 | uL/min | Rattus norvegicus | |||
19. | ALA2431363 | 17 | CLH | = | 65 | uL/min | ALA2434085 | uL/min | Rattus norvegicus | |||
20. | ALA2431364 | 18 | CLH | = | 42 | uL/min | ALA2434085 | uL/min | Rattus norvegicus |