Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	FXIa inhibitor 3f	3f	EC1.5	=	1.39	uM	ALA5141427			uM	Oryctolagus cuniculus
2.	FXIa inhibitor 3f	3f	Activity		0		ALA5141426		NA		Oryctolagus cuniculus
3.	FXIa inhibitor 3f	3f	Activity		0		ALA5141425		NA		Oryctolagus cuniculus
4.	FXIa inhibitor 3f	3f	FC	=	3.21		ALA5141424				Oryctolagus cuniculus
5.	FXIa inhibitor 3f	3f	FC	=	1.99		ALA5141423				Oryctolagus cuniculus
6.	ALA5203768	93d	IC50	=	8.94	uM	ALA5127331	5.05		nM	Oryctolagus cuniculus
7.	ALA5184389	93c	IC50	=	8.99	uM	ALA5127331	5.05		nM	Oryctolagus cuniculus
8.	ALA5180288	76f	IC50	=	1696	ug ml-1	ALA5127326			ug.mL-1	Oryctolagus cuniculus
9.	ALA5187332	76d	IC50	=	17.96	ug ml-1	ALA5127326			ug.mL-1	Oryctolagus cuniculus
10.	Apixaban	apixaban	Time	=	10	s	ALA5127307			hr	Oryctolagus cuniculus
11.	ALA5201923	37c	Time	=	9.5	s	ALA5127307			hr	Oryctolagus cuniculus
12.	ALA5198908	37b	Time	=	8.8	s	ALA5127307			hr	Oryctolagus cuniculus
13.	ALA5195103	37a	Time	=	10.2	s	ALA5127307			hr	Oryctolagus cuniculus
14.	ALA2043330	22, 3',4'-O-dimethylquercetin	Time	=	58.7	s	ALA5127307			hr	Oryctolagus cuniculus
15.	ALA2043332	24, 5,7-O-dimethylquercetin	Time	=	67.6	s	ALA5127307			hr	Oryctolagus cuniculus
16.	ALA312163	33	Time	=	72.6	s	ALA5127307			hr	Oryctolagus cuniculus
17.	Azaleatin	D6	Time	=	49.2	s	ALA5127307			hr	Oryctolagus cuniculus
18.	ALA2043330	22, 3',4'-O-dimethylquercetin	Time	=	5.8	s	ALA5127306			hr	Oryctolagus cuniculus
19.	ALA2043332	24, 5,7-O-dimethylquercetin	Time	=	6.9	s	ALA5127306			hr	Oryctolagus cuniculus
20.	ALA312163	33	Time	=	6.8	s	ALA5127306			hr	Oryctolagus cuniculus