# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1996510 | SID103905057 | AUC | = | 85 | ng/g.hr | ALA2156166 | ng/g.hr | Rattus norvegicus | |||
2. | ALA3120265 | 4 | CL | = | 41 | ml/min.kg | ALA3123446 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA3120265 | 4 | Vdss | = | 37 | L/Kg | ALA3123444 | L.kg-1 | Rattus norvegicus | |||
4. | ALA2158990 | 2 | Drug uptake | = | 0.016 | 10'-7M | ALA3129615 | 10'-7M | Rattus norvegicus | |||
5. | ALA3526474 | [14]apixaban | Radiolabel recovery | 0 | ALA3537783 | Not detected assumed BLQ | Rattus norvegicus | |||||
6. | ALA3526474 | [14]apixaban | Tmax | = | 1 | hr | ALA3537806 | hr | Rattus norvegicus | |||
7. | ALA3526474 | [14]apixaban | Cmax | = | 1180 | ngequiv/g | ALA3537810 | ngequiv/g | Rattus norvegicus | |||
8. | ALA3526474 | [14]apixaban | beta t1/2 | = | 2.9 | hr | ALA3540718 | hr | Rattus norvegicus | |||
9. | ALA3526474 | [14]apixaban | AUCt | = | 1940 | ngequiv.hr/g | ALA3540636 | ngequiv.hr/g | Rattus norvegicus | |||
10. | ALA3526474 | [14]apixaban | Radiolabel recovery | = | 1.18 | ugequiv/g | ALA3527946 | ugequiv/g | Rattus norvegicus | |||
11. | ALA3526474 | [14]apixaban | Radiolabel recovery | = | 0.08 | ugequiv/g | ALA3536898 | ugequiv/g | Rattus norvegicus | |||
12. | ALA3526474 | [14]apixaban | Radiolabel recovery | = | 0.88 | ugequiv/g | ALA3535821 | ugequiv/g | Rattus norvegicus | |||
13. | ALA3526474 | [14]apixaban | Radiolabel recovery | 0 | ALA3534245 | Not detected assumed BLQ | Rattus norvegicus | |||||
14. | ALA3526474 | [14]apixaban | Radiolabel recovery | = | 1.44 | ugequiv/g | ALA3541953 | ugequiv/g | Rattus norvegicus | |||
15. | ALA3526474 | [14]apixaban | Radiolabel recovery | = | 1.3 | ugequiv/g | ALA3540075 | ugequiv/g | Rattus norvegicus | |||
16. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 16.1 | ngequiv/ml | ALA3529443 | ngequiv/ml | Rattus norvegicus | |||
17. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 9.5 | ngequiv/ml | ALA3528078 | ngequiv/ml | Rattus norvegicus | |||
18. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 22.1 | ngequiv/ml | ALA3527878 | ngequiv/ml | Rattus norvegicus | |||
19. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 35.7 | ngequiv/ml | ALA3528069 | ngequiv/ml | Rattus norvegicus | |||
20. | ALA3527012 | [14C]CS-1036 | Radiolabel recovery | = | 5.27 | ngequiv/ml | ALA3530725 | ngequiv/ml | Rattus norvegicus |