# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Valacyclovir Hydrochloride Hydrate | VALACYCLOVIR HYDROCHLORIDE | Km | = | 1.2 | mM | ALA3527982 | nM | Rattus norvegicus | |||
2. | Apixaban | apixaban | Papp | = | 170 | nm/s | ALA3538531 | nm/s | Rattus norvegicus | |||
3. | Apixaban | apixaban | Papp | = | 73 | nm/s | ALA3538287 | nm/s | Rattus norvegicus | |||
4. | Glyburide | 2 | Activity | = | 32 | % | ALA3528377 | % | Rattus norvegicus | |||
5. | Glyburide | 2 | Activity | = | 25 | % | ALA3528376 | % | Rattus norvegicus | |||
6. | Glyburide | 2 | Peff | 0 | ALA3528375 | Dose-dependent effect | Rattus norvegicus | |||||
7. | Glyburide | 2 | Drugabsorption | 0 | ALA3528374 | Active | Rattus norvegicus | |||||
8. | Glyburide | 2 | Drug excretion | = | 0.02 | % | ALA3528373 | % | Rattus norvegicus | |||
9. | Glyburide | 2 | Peff | 0 | ALA3528372 | permeable | Rattus norvegicus | |||||
10. | Glyburide | 2 | Drugabsorption | = | 42 | % | ALA3528371 | % | Rattus norvegicus | |||
11. | Glyburide | 2 | Drugabsorption | = | 35 | % | ALA3528370 | % | Rattus norvegicus | |||
12. | Temocapril | Temocapril | Drug uptake | = | 1.83 | nmol/g | ALA3540701 | nmol/g | Rattus norvegicus | |||
13. | Temocapril | Temocapril | CL(app) | = | 1.59 | uL/min | ALA3540415 | uL/min | Rattus norvegicus | |||
14. | Temocapril | Temocapril | Peff | = | 4.56 | 10'-3cm/min | ALA3537185 | 10'-3cm/min | Rattus norvegicus | |||
15. | Temocapril | Temocapril | Peff | = | 3.43 | 10'-3cm/min | ALA3540412 | 10'-3cm/min | Rattus norvegicus | |||
16. | Temocapril | Temocapril | CL | = | 34.4 | uL/min | ALA3540413 | uL/min | Rattus norvegicus | |||
17. | Temocapril | Temocapril | CL | = | 35.4 | uL/min | ALA3540414 | uL/min | Rattus norvegicus | |||
18. | Temocaprilat | 24c | CL(app) | = | 1.87 | uL/min | ALA3540415 | uL/min | Rattus norvegicus | |||
19. | Temocapril | Temocapril | Peff | = | 3.25 | 10'-3cm/min | ALA3540416 | 10'-3cm/min | Rattus norvegicus | |||
20. | Temocapril | Temocapril | CL | = | 43.2 | uL/min | ALA3540418 | uL/min | Rattus norvegicus |