# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3087669 | 3h | INH | = | 23 | % | ALA3088778 | % | Cavia porcellus | |||
2. | ALA3087669 | 3h | INH | = | 33 | % | ALA3088777 | % | Cavia porcellus | |||
3. | ALA3087669 | 3h | Activity | 0 | ALA3088779 | Non-toxic | Cavia porcellus | |||||
4. | ALA2401841 | (R)-MHM | %max | = | 66 | % | ALA2406651 | % | Cavia porcellus | |||
5. | ALA2401842 | (S)-MHM | %max | = | 13 | % | ALA2406653 | % | Cavia porcellus | |||
6. | ALA2401841 | (R)-MHM | EC50 | = | 0.56 | uM | ALA2406652 | 6.25 | nM | Cavia porcellus | ||
7. | ALA3806205 | 3d-P | Activity | 0 | ALA3807363 | Toxic | Cavia porcellus | |||||
8. | ALA3806205 | 3d-P | Activity | 0 | ALA3807362 | Toxic | Cavia porcellus | |||||
9. | ALA3806205 | 3d-P | Activity | 0 | ALA3807361 | Non-toxic | Cavia porcellus | |||||
10. | Siponimod (BAF312) | 32, BAF312, Siponimod | Activity | 0 | ALA3807360 | Toxic | Cavia porcellus | |||||
11. | Siponimod (BAF312) | 32, BAF312, Siponimod | Activity | 0 | ALA3807359 | Toxic | Cavia porcellus | |||||
12. | ALA3806205 | 3d-P | Activity | 0 | ALA3807359 | Non-toxic | Cavia porcellus | |||||
13. | FTY720 (R)-Phosphate | 2 | Activity | 0 | ALA3807358 | Toxic | Cavia porcellus | |||||
14. | FTY720 (R)-Phosphate | 2 | Activity | = | 32 | bpm | ALA3807357 | bpm | Cavia porcellus | |||
15. | ALA3275396 | 15, cis-diastereomeric mixture | FC | = | 1.5 | ALA3284501 | Cavia porcellus | |||||
16. | Quinidine | quinidine | Activity | 0 | ALA3285874 | Dose-dependent effect | Cavia porcellus | |||||
17. | ALA3275400 | 19 | Activity | 0 | ALA3285874 | Dose-dependent effect | Cavia porcellus | |||||
18. | ALA3275398 | 17, cis-diastereomeric mixture | Activity | 0 | ALA3285874 | Dose-dependent effect | Cavia porcellus | |||||
19. | ALA3275400 | 19 | Activity | = | -23 | % | ALA3285600 | % | Cavia porcellus | |||
20. | ALA3275400 | 19 | Activity | = | -57.8 | % | ALA3285599 | % | Cavia porcellus |