# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5173333 | 52 | INH | 0 | ALA5138553 | NA | % | Homo sapiens | ||||
2. | S-(5′-Adenosyl)-L-homocysteine | SAH | IC50 | = | 0.7 | uM | ALA5138548 | 6.16 | nM | Homo sapiens | ||
3. | CM272 | 12; CM-272 | IC50 | = | 1.2 | uM | ALA5138548 | 5.92 | nM | Homo sapiens | ||
4. | ALA5178532 | 53 | IC50 | = | 0.3 | uM | ALA5138548 | 6.52 | nM | Homo sapiens | ||
5. | ALA5189142 | 68 | IC50 | = | 1.3 | uM | ALA5138548 | 5.89 | nM | Homo sapiens | ||
6. | ALA5187655 | 69 | IC50 | = | 12.8 | uM | ALA5138548 | 4.89 | nM | Homo sapiens | ||
7. | ALA5192832 | 1 | IC50 | = | 18.2 | uM | ALA5138548 | 4.74 | nM | Homo sapiens | ||
8. | ALA5191050 | 35 | IC50 | = | 6.6 | uM | ALA5138548 | 5.18 | nM | Homo sapiens | ||
9. | Ibiglustat | VENGLUSTAT | INH | = | 50 | % | ALA5119864 | % | Homo sapiens | |||
10. | Ibiglustat | VENGLUSTAT | INH | 0 | ALA5119827 | NA | % | Homo sapiens | ||||
11. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401534 | Not Active | % | Homo sapiens | ||||
12. | ALA4588672 | 7d | INH | = | 10 | % | ALA4391129 | % | Homo sapiens | |||
13. | ALA4797205 | 1 | Activity | 0 | ALA4736938 | Not Active | Homo sapiens | |||||
14. | ALA4761671 | F1v69 | FC | = | 2 | ALA4682610 | Homo sapiens | |||||
15. | ALA4782068 | 3b | FC | = | 6.1 | ALA4682610 | Homo sapiens | |||||
16. | ALA4797538 | 3a | FC | = | 8.8 | ALA4682610 | Homo sapiens | |||||
17. | ALA4782068 | 3b | Activity | 0 | ALA4682609 | Dose-dependent effect | Homo sapiens | |||||
18. | ALA4757027 | 4a | Activity | 0 | ALA4682609 | Dose-dependent effect | Homo sapiens | |||||
19. | ALA4748200 | 4b | Activity | 0 | ALA4682609 | Dose-dependent effect | Homo sapiens | |||||
20. | ALA4797538 | 3a | Activity | 0 | ALA4682609 | Dose-dependent effect | Homo sapiens |