# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | [³H]strychnine | Strychnine | IC50 | = | 150 | nM | ALA4342369 | 6.82 | nM | Homo sapiens | ||
2. | ALA4447664 | 1 | IC50 | = | 1000 | nM | ALA4342369 | 6.00 | nM | Homo sapiens | ||
3. | ALA4518537 | 2 | IC50 | = | 710 | nM | ALA4342369 | 6.15 | nM | Homo sapiens | ||
4. | [³H]strychnine | Strychnine | IC50 | = | 51 | nM | ALA4342371 | 7.29 | nM | Homo sapiens | ||
5. | ALA4447664 | 1 | IC50 | = | 194 | nM | ALA4342371 | 6.71 | nM | Homo sapiens | ||
6. | ALA4518537 | 2 | IC50 | = | 173 | nM | ALA4342371 | 6.76 | nM | Homo sapiens | ||
7. | [³H]strychnine | Strychnine | Ki | = | 123 | nM | ALA4342368 | 6.91 | nM | Homo sapiens | ||
8. | ALA4447664 | 1 | Ki | = | 741 | nM | ALA4342368 | 6.13 | nM | Homo sapiens | ||
9. | ALA4518537 | 2 | Ki | = | 91 | nM | ALA4342368 | 7.04 | nM | Homo sapiens | ||
10. | [³H]strychnine | Strychnine | pIC50 | = | 6.82 | ALA4342369 | 6.82 | nM | Homo sapiens | |||
11. | ALA4447664 | 1 | pIC50 | = | 6 | ALA4342369 | 6.00 | nM | Homo sapiens | |||
12. | ALA4518537 | 2 | pIC50 | = | 6.15 | ALA4342369 | 6.15 | nM | Homo sapiens | |||
13. | ALA4228372 | 54 | EC50 | = | 0.06 | nM | ALA4219947 | 10.22 | nM | Homo sapiens | ||
14. | ALA4226150 | 53 | EC50 | = | 0.001 | nM | ALA4219947 | nM | Homo sapiens | |||
15. | ALA4227144 | 52 | EC50 | = | 0 | nM | ALA4219947 | nM | Homo sapiens | |||
16. | ALA4227297 | 51 | EC50 | = | 0.43 | nM | ALA4219947 | 9.37 | nM | Homo sapiens | ||
17. | ALA4226572 | 49 | Activity | = | 110 | % | ALA4219946 | % | Homo sapiens | |||
18. | ALA4074873 | 20-AM-1488 | Emax | = | 102.4 | % | ALA4219934 | % | Homo sapiens | |||
19. | ALA4074873 | 20-AM-1488 | EC50 | = | 0.327 | uM | ALA4219928 | 6.49 | nM | Homo sapiens | ||
20. | ALA4070615 | 32; AM-3607 | EC50 | = | 32 | nM | ALA4219619 | 7.50 | nM | Homo sapiens |