# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | vaborbactam | 27, RPX7009 | MIC | = | 0.25 | ug ml-1 | ALA3579149 | ug.mL-1 | Klebsiella pneumoniae | |||
2. | ALA2236666 | LN-1255 | Ki | = | 1.36 | uM | ALA3061796 | 5.87 | nM | Klebsiella pneumoniae | ||
3. | ALA1673091 | penem 1 | Ki | = | 28.03 | uM | ALA3061796 | 4.55 | nM | Klebsiella pneumoniae | ||
4. | ALA1673092 | penem 2 | Ki | = | 106.21 | uM | ALA3061796 | nM | Klebsiella pneumoniae | |||
5. | clavulanic acid | Clavulanic acid | Ki | = | 25.36 | uM | ALA3061796 | 4.60 | nM | Klebsiella pneumoniae | ||
6. | ALA1795571 | 6a, Isomer A | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
7. | ALA1795571 | 6a, Isomer A | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
8. | ALA1795570 | 5b | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
9. | ALA1795569 | 5a | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
10. | ALA1795568 | 4 | IC50 | = | 27 | uM | ALA1799219 | 4.57 | nM | Klebsiella pneumoniae | ||
11. | ALA1795567 | 3b | IC50 | = | 22 | uM | ALA1799219 | 4.66 | nM | Klebsiella pneumoniae | ||
12. | ALA1795566 | 3a | IC50 | > | 12.5 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
13. | ALA1795565 | 3 | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
14. | ALA1795564 | 2a, IsomerA | IC50 | = | 15 | uM | ALA1799219 | 4.82 | nM | Klebsiella pneumoniae | ||
15. | ALA1795564 | 2a, IsomerA | IC50 | = | 25 | uM | ALA1799219 | 4.60 | nM | Klebsiella pneumoniae | ||
16. | ALA1795563 | 1 | IC50 | > | 50 | uM | ALA1799219 | nM | Klebsiella pneumoniae | |||
17. | ALA1089781 | I, DSABA | IC50 | = | 0.57 | uM | ALA1106171 | 6.24 | nM | Klebsiella pneumoniae |