# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MK-4827 (Niraparib) | 56, MK-4827 | CC50 | = | 23 | nM | ALA3429606 | nM | Homo sapiens | |||
2. | ALA4060134 | 41 | Imax | = | 45.8 | % | ALA4013013 | % | Homo sapiens | |||
3. | ALA4060134 | 41 | pGI50 | = | 5.2 | ALA4012985 | nM | Homo sapiens | ||||
4. | ALA4060134 | 41 | Imax | = | 78.1 | % | ALA4012962 | % | Homo sapiens | |||
5. | ALA4060134 | 41 | pGI50 | = | 7.7 | ALA4012933 | nM | Homo sapiens | ||||
6. | Rucaparib | 63, AG-014699 | IC50 | = | 23.561 | uM | ALA2363194 | 4.63 | nM | Homo sapiens | ||
7. | CCT 018159 | 3a CCT018159 | IC50 | = | 10.234 | uM | ALA2363194 | 4.99 | nM | Homo sapiens | ||
8. | TW-37 | 5, TW-37 | IC50 | = | 1.475 | uM | ALA2363194 | 5.83 | nM | Homo sapiens | ||
9. | JNJ-26854165 (Serdemetan) | SID137276015 | IC50 | = | 30.016 | uM | ALA2363194 | 4.52 | nM | Homo sapiens | ||
10. | PF-4708671 | SID137275978 | IC50 | = | 248.292 | uM | ALA2363194 | nM | Homo sapiens | |||
11. | Avagacestat | 80 BMS-708163 | IC50 | = | 347.238 | uM | ALA2363194 | nM | Homo sapiens | |||
12. | EHT 1864 | SID137275837 | IC50 | = | 189.931 | uM | ALA2363194 | nM | Homo sapiens | |||
13. | CCT007093 | A17 | IC50 | = | 75.509 | uM | ALA2363194 | 4.12 | nM | Homo sapiens | ||
14. | AZD6482 | AZD-6482 | IC50 | = | 156.424 | uM | ALA2363194 | nM | Homo sapiens | |||
15. | ALA1614701 | AZD-6244 | IC50 | = | 14.517 | uM | ALA2363194 | 4.84 | nM | Homo sapiens | ||
16. | SB590885 | 33, SB-590885 | IC50 | = | 209.126 | uM | ALA2363194 | nM | Homo sapiens | |||
17. | PD0325901 | 34, PD-0325901 | IC50 | = | 0.801 | uM | ALA2363194 | 6.10 | nM | Homo sapiens | ||
18. | AZD8055 | 10, AZD-8055 | IC50 | = | 23.847 | uM | ALA2363194 | 4.62 | nM | Homo sapiens | ||
19. | GDC-0941 | 17, GDC-0941 | IC50 | = | 87.279 | uM | ALA2363194 | 4.06 | nM | Homo sapiens | ||
20. | BEZ235 | SID124898663 | IC50 | = | 1.074 | uM | ALA2363194 | 5.97 | nM | Homo sapiens |