# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Methotrexate | 138 | IC50 | = | 110 | nM | ALA5138445 | 6.96 | nM | Trypanosoma cruzi | ||
2. | ALA334919 | 13 | Ki | = | 23 | nM | ALA5138444 | 7.64 | nM | Trypanosoma cruzi | ||
3. | ALA5197890 | 44 | Ki | = | 30 | nM | ALA5138444 | 7.52 | nM | Trypanosoma cruzi | ||
4. | ALA5208797 | 43 | Ki | = | 6.6 | nM | ALA5138443 | 8.18 | nM | Trypanosoma cruzi | ||
5. | ALA1165388 | 6b | Km | = | 1.45 | nM | ALA1167431 | nM | Trypanosoma cruzi | |||
6. | ALA1163286 | 6a | Km | = | 3.25 | nM | ALA1167431 | nM | Trypanosoma cruzi | |||
7. | ALA1165388 | 6b | Ki | = | 5.68 | nM | ALA1167430 | 8.25 | nM | Trypanosoma cruzi | ||
8. | ALA1163286 | 6a | Ki | = | 4.75 | nM | ALA1167430 | 8.32 | nM | Trypanosoma cruzi | ||
9. | trimetrexate | TMQ | Ki | = | 6.6 | nM | ALA1167426 | 8.18 | nM | Trypanosoma cruzi | ||
10. | ALA1164279 | 9 | Ki | = | 3.6 | nM | ALA1167426 | 8.44 | nM | Trypanosoma cruzi | ||
11. | ALA1164234 | 8 | Ki | = | 24.9 | nM | ALA1167426 | 7.60 | nM | Trypanosoma cruzi | ||
12. | ALA1165306 | 6d | Ki | = | 3.3 | nM | ALA1167426 | 8.48 | nM | Trypanosoma cruzi | ||
13. | ALA1165305 | 6c | Ki | = | 1.6 | nM | ALA1167426 | 8.80 | nM | Trypanosoma cruzi | ||
14. | ALA1165388 | 6b | Ki | = | 1.3 | nM | ALA1167426 | 8.89 | nM | Trypanosoma cruzi | ||
15. | ALA1163286 | 6a | Ki | = | 1.6 | nM | ALA1167426 | 8.80 | nM | Trypanosoma cruzi | ||
16. | trimetrexate | TMQ | IC50 | = | 20.2 | nM | ALA1167426 | 7.70 | nM | Trypanosoma cruzi | ||
17. | ALA1164279 | 9 | IC50 | = | 61 | nM | ALA1167426 | 7.21 | nM | Trypanosoma cruzi | ||
18. | ALA1164234 | 8 | IC50 | = | 422 | nM | ALA1167426 | 6.38 | nM | Trypanosoma cruzi | ||
19. | ALA1165306 | 6d | IC50 | = | 57.5 | nM | ALA1167426 | 7.24 | nM | Trypanosoma cruzi | ||
20. | ALA1165305 | 6c | IC50 | = | 27 | nM | ALA1167426 | 7.57 | nM | Trypanosoma cruzi |