# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Imipenem | Imipenem | IC50 | = | 0.15 | uM | ALA1247087 | 6.82 | nM | Pseudomonas aeruginosa | ||
2. | clavulanic acid | Clavulanic acid | IC50 | = | 0.1 | uM | ALA1247087 | 7.00 | nM | Pseudomonas aeruginosa | ||
3. | Sulbactam | 1 | IC50 | = | 0.37 | uM | ALA1247087 | 6.43 | nM | Pseudomonas aeruginosa | ||
4. | Tazobactam acid | 2 Tazobactam | IC50 | = | 0.06 | uM | ALA1247087 | 7.22 | nM | Pseudomonas aeruginosa | ||
5. | penicillin G | Benzylpenicillin | Km | = | 139 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
6. | Nitrocefin | nitrocefin | Km | = | 197 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
7. | Imipenem | Imipenem | Km | 0 | ALA1247085 | Not Determined | Pseudomonas aeruginosa | |||||
8. | ALA617 | Cephalothin | Km | = | 106 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
9. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Km | = | 229 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
10. | Cefotaxime acid | cefotaxime | Km | = | 63 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
11. | ALA158 | aztreonam | Km | = | 405 | uM | ALA1247085 | nM | Pseudomonas aeruginosa | |||
12. | penicillin G | Benzylpenicillin | Kcat/Km | = | 0.1 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
13. | Nitrocefin | nitrocefin | Kcat/Km | = | 0.15 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
14. | Imipenem | Imipenem | Kcat/Km | 0 | ALA1247086 | Not Determined | Pseudomonas aeruginosa | |||||
15. | ALA617 | Cephalothin | Kcat/Km | = | 0.1 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
16. | Ceftazidime (containing approximately 10% sodium carbonate) | CAZ | Kcat/Km | = | 0.13 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
17. | Cefotaxime acid | cefotaxime | Kcat/Km | = | 1.09 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
18. | ALA158 | aztreonam | Kcat/Km | = | 0.09 | /uM/s | ALA1247086 | /uM/s | Pseudomonas aeruginosa | |||
19. | penicillin G | Benzylpenicillin | Kcat | = | 13.5 | /s | ALA1247085 | /s | Pseudomonas aeruginosa | |||
20. | Nitrocefin | nitrocefin | Kcat | = | 29.3 | /s | ALA1247085 | /s | Pseudomonas aeruginosa |