# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA464946 | (4R,5R)-ATX | FC | = | 2 | ALA5146355 | Mus musculus | |||||
2. | ALA464946 | (4R,5R)-ATX | Activity | 0 | ALA5146354 | NA | Mus musculus | |||||
3. | ALA5203121 | 40 | IC50 | = | 1633 | nM | ALA5139130 | 5.79 | nM | Mus musculus | ||
4. | BKM120 | 15, NVP-BKM120 | IC50 | = | 832 | nM | ALA5139130 | 6.08 | nM | Mus musculus | ||
5. | ALA413 | Rapamycin | IC50 | = | 0.05 | nM | ALA4434258 | 10.30 | nM | Mus musculus | ||
6. | ALA4591064 | 2 | IC50 | = | 0.274 | nM | ALA4434258 | 9.56 | nM | Mus musculus | ||
7. | ALA4563398 | 5 | IC50 | = | 153 | nM | ALA4434258 | 6.82 | nM | Mus musculus | ||
8. | ALA4529771 | 6 | IC50 | = | 0.17 | nM | ALA4434258 | 9.77 | nM | Mus musculus | ||
9. | ALA4465976 | 12 | IC50 | = | 0.374 | nM | ALA4434258 | 9.43 | nM | Mus musculus | ||
10. | ALA4580738 | 15 | IC50 | = | 3.2 | nM | ALA4434258 | 8.49 | nM | Mus musculus | ||
11. | (S)-3-Methyl-4-(7-((R)-3-methylmorpholino)-2-(1H-pyrazol-3-yl)thiazolo[5,4-d]pyrimidin-5-yl)morpholine | 7 | INH | 0 | ALA4381606 | Dose-dependent effect | % | Mus musculus | ||||
12. | ALA4442382 | 14 | IC50 | = | 6.3 | nM | ALA4381568 | 8.20 | nM | Mus musculus | ||
13. | ALA4470066 | 13 | IC50 | = | 3.7 | nM | ALA4381568 | 8.43 | nM | Mus musculus | ||
14. | ALA4468727 | 12 | IC50 | = | 92 | nM | ALA4381568 | 7.04 | nM | Mus musculus | ||
15. | ALA4522946 | 11 | IC50 | = | 134 | nM | ALA4381568 | 6.87 | nM | Mus musculus | ||
16. | ALA4562597 | 10 | IC50 | = | 2.7 | nM | ALA4381568 | 8.57 | nM | Mus musculus | ||
17. | ALA4451234 | 9 | IC50 | = | 5.3 | nM | ALA4381568 | 8.28 | nM | Mus musculus | ||
18. | ALA4538499 | 8 | IC50 | = | 603 | nM | ALA4381568 | 6.22 | nM | Mus musculus | ||
19. | (S)-3-Methyl-4-(7-((R)-3-methylmorpholino)-2-(1H-pyrazol-3-yl)thiazolo[5,4-d]pyrimidin-5-yl)morpholine | 7 | IC50 | = | 5.6 | nM | ALA4381568 | 8.25 | nM | Mus musculus | ||
20. | ALA4566380 | 6 | IC50 | = | 7.8 | nM | ALA4381568 | 8.11 | nM | Mus musculus |