# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Wedelolactone | 1a | INH | = | 6 | % | ALA1660355 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
2. | ALA1649743 | 22 | INH | = | 5 | % | ALA1660357 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
3. | ALA1649742 | 15 | INH | = | 14 | % | ALA1660357 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
4. | ALA1451483 | SID26749737 | INH | = | 27 | % | ALA1660357 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
5. | ALA1649741 | 8 | INH | = | 33 | % | ALA1660357 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
6. | ALA1649740 | 5 | INH | = | 16 | % | ALA1660357 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
7. | ALA1649740 | 5 | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
8. | ALA1649741 | 8 | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
9. | Wedelolactone | 1a | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
10. | ALA1451483 | SID26749737 | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
11. | ALA1649742 | 15 | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
12. | ALA1649743 | 22 | INH | = | 70 | % | ALA1660356 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
13. | ALA1649743 | 22 | INH | = | 75 | % | ALA1660354 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
14. | ALA1649742 | 15 | INH | = | 79 | % | ALA1660354 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
15. | ALA1451483 | SID26749737 | INH | = | 32 | % | ALA1660354 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
16. | ALA1649741 | 8 | INH | = | 43 | % | ALA1660354 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
17. | ALA1649740 | 5 | INH | = | 65 | % | ALA1660354 | % | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | |||
18. | ALA1649743 | 22 | IC50 | = | 2.62 | uM | ALA1660353 | 5.58 | nM | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | ||
19. | ALA1649742 | 15 | IC50 | = | 1.96 | uM | ALA1660353 | 5.71 | nM | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) | ||
20. | ALA1451483 | SID26749737 | IC50 | = | 2.73 | uM | ALA1660353 | 5.56 | nM | Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM4680) |