# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4639128 | 62 | pIC50 | = | 4.4 | ALA5303911 | 4.40 | nM | Homo sapiens | |||
2. | GSK620 | 1; 20 | pIC50 | < | 4.3 | ALA5303861 | nM | Homo sapiens | ||||
3. | GSK046 | 15; GSK046 | pIC50 | < | 4.3 | ALA5303812 | nM | Homo sapiens | ||||
4. | MK-8245 | MK-8245 | Activity | 0 | ALA2154722 | Not Active | Homo sapiens | |||||
5. | MK-8245 | MK-8245 | Activity | 0 | ALA2154254 | Active | Homo sapiens | |||||
6. | digoxin | Digoxin | Ratio | = | 0.66 | ALA3528696 | Homo sapiens | |||||
7. | digoxin | Digoxin | Ratio | = | 0.63 | ALA3528699 | Homo sapiens | |||||
8. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Ratio | = | 6.7 | ALA3528696 | Homo sapiens | |||||
9. | ALA1496 | Rosuvastatin | Ratio | = | 3.4 | ALA3528696 | Homo sapiens | |||||
10. | midazolam | Midazolam | Ratio | = | 0.92 | ALA3528696 | Homo sapiens | |||||
11. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Ratio | = | 2.2 | ALA3528699 | Homo sapiens | |||||
12. | ALA1496 | Rosuvastatin | Ratio | = | 1.9 | ALA3528699 | Homo sapiens | |||||
13. | midazolam | Midazolam | Ratio | = | 0.92 | ALA3528699 | Homo sapiens | |||||
14. | Dolutegravir (GSK1349572) | DOLUTEGRAVIR | IC50 | > | 100 | uM | ALA3537109 | nM | Homo sapiens | |||
15. | Paclitaxel | Paclitaxel | IC50 | = | 0.28 | uM | ALA3411291 | 6.55 | nM | Homo sapiens | ||
16. | Vinblastine | Vinblastine | IC50 | = | 46.8 | uM | ALA3411291 | 4.33 | nM | Homo sapiens | ||
17. | Paclitaxel | Paclitaxel | INH | = | 16.4 | % | ALA3411295 | % | Homo sapiens | |||
18. | Chlorambucil | chlorambucil (CBL) | Activity | = | 18.8 | % | ALA3411289 | % | Homo sapiens | |||
19. | Cladribine | 25 | Activity | = | 15.9 | % | ALA3411289 | % | Homo sapiens | |||
20. | Irinotecan | Irinotecan | Activity | = | 93.3 | % | ALA3411289 | % | Homo sapiens |