| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4217988 | 5; PF-06456384 | Ratio | = | 3.6 | ALA4179801 | Homo sapiens | |||||
| 2. |  ALA421 | 18 | Km | = | 1.73 | uM | ALA4049523 | nM | Homo sapiens | |||
| 3. |  Pravastatin | 2 (pravastatin) | Km | = | 6.25 | uM | ALA4049523 | nM | Homo sapiens | |||
| 4. |  estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 0.1 | uM | ALA4049523 | nM | Homo sapiens | |||
| 5. | Pravastatin | 2 (pravastatin) | Km | = | 225 | uM | ALA4049522 | nM | Homo sapiens | |||
| 6. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Km | = | 29.9 | uM | ALA4049522 | nM | Homo sapiens | |||
| 7. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | < | 1 | % | ALA4049521 | % | Homo sapiens | |||
| 8. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 79 | % | ALA4049520 | % | Homo sapiens | |||
| 9. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | < | 1 | % | ALA4049519 | % | Homo sapiens | |||
| 10. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 21 | % | ALA4049518 | % | Homo sapiens | |||
| 11. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | 0 | ALA4049517 | Not Active | Homo sapiens | |||||
| 12. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | 0 | ALA4049516 | Active | Homo sapiens | |||||
| 13. |  Prostaglandin E₂ | PGE2 | Drug uptake | 0 | ALA4049515 | Active | Homo sapiens | |||||
| 14. | Prostaglandin E₂ | PGE2 | Drug uptake | 0 | ALA4049514 | Active | Homo sapiens | |||||
| 15. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 14 | % | ALA4049464 | % | Homo sapiens | |||
| 16. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 17.8 | % | ALA4049465 | % | Homo sapiens | |||
| 17. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 2.39 | uL | ALA4049466 | uL | Homo sapiens | |||
| 18. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | Drug uptake | = | 0.198 | uL | ALA4049467 | uL | Homo sapiens | |||
| 19. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | FC | < | 2 | ALA4049468 | Homo sapiens | |||||
| 20. | estrone-3-sulphate | estrone-3-O-sulfamate (EMATE) | FC | < | 2 | ALA4049469 | Homo sapiens |
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