# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3398252 | 2 | Drug metabolism | 0 | ALA3398975 | metabolite_notdetected | Homo sapiens | |||||
2. | Raltegravir (MK-0518) | 1, raltegravir | Drug metabolism | 0 | ALA3398975 | metabolite_detected | Homo sapiens | |||||
3. | ALA3398252 | 2 | Activity | 0 | ALA3398989 | Not Active | Homo sapiens | |||||
4. | ALA3398252 | 2 | IC50 | > | 300 | uM | ALA3399066 | nM | Homo sapiens | |||
5. | Naproxen | naproxen | Drug metabolism | 0 | ALA4133167 | Metabolite_Detected | Homo sapiens | |||||
6. | Ibuprofen | ibuprofen | Drug metabolism | 0 | ALA4133167 | Metabolite_Detected | Homo sapiens | |||||
7. | Diclofenac | 25 (Diclofenac) | Drug metabolism | 0 | ALA4133167 | Metabolite_Notdetected | Homo sapiens | |||||
8. | ALA4162056 | 9d | Drug metabolism | 0 | ALA4133167 | Metabolite_Notdetected | Homo sapiens | |||||
9. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | Drug metabolism | 0 | ALA3535222 | metabolite_detected | Homo sapiens | |||||
10. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | Drug metabolism | 0 | ALA3541742 | metabolite_detected | Homo sapiens | |||||
11. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | VmaxH | = | 254.5 | pmol/min/g | ALA3531843 | pmol/min/g | Homo sapiens | |||
12. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | CL(high) | = | 42.4 | uL/min/g | ALA3531844 | mL.min-1.g-1 | Homo sapiens | |||
13. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | Drug metabolism | 0 | ALA3535215 | metabolite_not_detected | Homo sapiens | |||||
14. | Mycophenolic acid | MPA | Km | = | 160 | uM | ALA3531842 | nM | Homo sapiens | |||
15. | 2,6-Diisopropylphenol | 1 (Propofol) | Km | = | 41 | uM | ALA3531842 | nM | Homo sapiens | |||
16. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | VmaxL | = | 340.4 | pmol/min/g | ALA3531843 | pmol/min/g | Homo sapiens | |||
17. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | CL(low) | = | 0.8 | uL/min/g | ALA3531844 | mL.min-1.g-1 | Homo sapiens | |||
18. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | KmH | = | 6 | uM | ALA3531842 | uM | Homo sapiens | |||
19. | 1-pheny-3-methyl-5-pyrazolone | Edaravone | KmL | = | 419.4 | uM | ALA3531842 | uM | Homo sapiens | |||
20. | Mycophenolic acid | MPA | CL free | = | 3.13 | ml/min/g | ALA3539807 | mL.min-1.g-1 | Homo sapiens |