| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1201053 | [3H]Ipratropium | Drug uptake | = | 52.9 | % | ALA3541382 | % | Rattus norvegicus | |||
| 2. |  4-(2-Aminoethyl)benzene-1,2-diol | Dopamine | Km | = | 650 | uM | ALA3531528 | nM | Rattus norvegicus | |||
| 3. |  MPP⁺ | 1 | Km | = | 17 | uM | ALA3531528 | nM | Rattus norvegicus | |||
| 4. | ALA1201053 | [3H]Ipratropium | Drug uptake | 0 | ALA3531422 | Dose-dependent effect | Rattus norvegicus | |||||
| 5. | ALA1201053 | [3H]Ipratropium | Drug uptake | 0 | ALA3531420 | tde | Rattus norvegicus | |||||
| 6. | ALA1201053 | [3H]Ipratropium | Vmax | = | 7.33 | pmol | ALA3531426 | pmol | Rattus norvegicus | |||
| 7. |  ALA3526300 | [3H]Tiotropium | FC | = | 3 | ALA3531416 | Rattus norvegicus | |||||
| 8. | ALA1201053 | [3H]Ipratropium | FC | = | 4.5 | ALA3531418 | Rattus norvegicus | |||||
| 9. | ALA1201053 | [3H]Ipratropium | FC | = | 34 | ALA3531416 | Rattus norvegicus | |||||
| 10. | ALA1201053 | [3H]Ipratropium | Km | = | 0.143 | uM | ALA3531424 | nM | Rattus norvegicus | |||
| 11. | ALA1201053 | [3H]Ipratropium | Drug uptake | = | 2.71 | % | ALA3541384 | % | Rattus norvegicus | |||
| 12. | ALA1201053 | [3H]Ipratropium | Drug uptake | = | 15.4 | % | ALA3541383 | % | Rattus norvegicus | |||
| 13. |  PF-04971729 | 4, PF-04971729 | INH | 0 | ALA1771937 | Not Active | % | Rattus norvegicus | ||||
| 14. |  Cimetidine | cimetidine | Ki | = | 9.4 | uM | ALA2078555 | 5.03 | inhibitor [Ki=9.4uM] | nM | Rattus norvegicus | |
| 15. |  guanidine | 14 | Ki | = | 713.6 | uM | ALA2078555 | inhibitor [Ki=713.6uM] | nM | Rattus norvegicus | ||
| 16. |  [³H]thiamine | 1, thiamine | Ki | = | 646 | uM | ALA2078135 | inhibitor [Ki=646uM] | nM | Rattus norvegicus | ||
| 17. |  Quinine | 10a | Ki | = | 55 | uM | ALA2078597 | 4.26 | inhibitor [Ki=55uM] | nM | Rattus norvegicus | |
| 18. |  tetraethylammonium | 1 | Ki | = | 52.2 | uM | ALA2078602 | 4.28 | inhibitor [Ki=52.2uM] | nM | Rattus norvegicus | |
| 19. |  Nicotine | 2 | Ki | = | 50.5 | uM | ALA2078555 | 4.30 | inhibitor [Ki=50.5uM] | nM | Rattus norvegicus | |
| 20. |  N-Methylnicotinamide | 15 | Ki | = | 403.4 | uM | ALA2078555 | inhibitor [Ki=403.4uM] | nM | Rattus norvegicus |
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