# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Pemetrexed | 2 (LY-231514) | IC50 | = | 13.2 | nM | ALA3412692 | 7.88 | nM | Homo sapiens | ||
2. | ALA3409337 | 11 | IC50 | > | 1000 | nM | ALA3412692 | nM | Homo sapiens | |||
3. | ALA3409336 | 10 | IC50 | = | 57.4 | nM | ALA3412692 | 7.24 | nM | Homo sapiens | ||
4. | ALA3409335 | 9 | IC50 | = | 141 | nM | ALA3412692 | 6.85 | nM | Homo sapiens | ||
5. | ALA3409334 | 8 | IC50 | = | 312 | nM | ALA3412692 | 6.51 | nM | Homo sapiens | ||
6. | ALA3407519 | 7 | IC50 | = | 80.2 | nM | ALA3412692 | 7.10 | nM | Homo sapiens | ||
7. | ALA2426245 | 5 | IC50 | > | 1000 | nM | ALA3412692 | nM | Homo sapiens | |||
8. | ALA590740 | 1 | IC50 | = | 43.4 | nM | ALA3412692 | 7.36 | nM | Homo sapiens | ||
9. | ALA3335607 | 13 | Ki | = | 2.9 | uM | ALA3382016 | 5.54 | nM | Homo sapiens | ||
10. | ALA1834488 | 3 | IC50 | = | 3.34 | nM | ALA3387475 | 8.48 | nM | Homo sapiens | ||
11. | ALA3335603 | 9 | IC50 | > | 1000 | nM | ALA3387475 | nM | Homo sapiens | |||
12. | ALA3335604 | 10 | IC50 | > | 1000 | nM | ALA3387475 | nM | Homo sapiens | |||
13. | ALA3335605 | 11 | IC50 | > | 1000 | nM | ALA3387475 | nM | Homo sapiens | |||
14. | ALA3335606 | 12 | IC50 | > | 1000 | nM | ALA3387475 | nM | Homo sapiens | |||
15. | ALA3335607 | 13 | IC50 | > | 1000 | nM | ALA3387475 | nM | Homo sapiens | |||
16. | [³H]methotrexate | 138 | IC50 | = | 120.5 | nM | ALA3387475 | 6.92 | nM | Homo sapiens | ||
17. | Pemetrexed | 2 (LY-231514) | IC50 | = | 13.2 | nM | ALA3387475 | 7.88 | nM | Homo sapiens | ||
18. | Raltitrexed | 8a | IC50 | = | 99.5 | nM | ALA3387475 | 7.00 | nM | Homo sapiens | ||
19. | ALA3335605 | 11 | Ki | = | 1.6 | uM | ALA3382016 | 5.80 | nM | Homo sapiens | ||
20. | ALA1834488 | 3 | Ki | = | 0.33 | uM | ALA3382016 | 6.48 | nM | Homo sapiens |