# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | BI 605906 | BI605906 | % Ctrl | 100 | % | ALA4887316 | Not Active | % | Homo sapiens | |||
2. | ALA4097778 | 16h | pIC50 | 6 | ALA4885420 | nM | Homo sapiens | |||||
3. | ALA4549667 | EUB0000720 | pIC50 | 6 | ALA4885134 | nM | Homo sapiens | |||||
4. | ALA4088216 | 14 | pIC50 | 6 | ALA4884843 | nM | Homo sapiens | |||||
5. | GSK840 | 52; GSK'840 | IC50 | = | 0.3 | nM | ALA4425337 | 9.52 | nM | Homo sapiens | ||
6. | ALA2205766 | 14, CZC24758 | pIC50 | < | 5 | ALA2214442 | nM | Homo sapiens | ||||
7. | ALA3628628 | 5 | INH | = | 27.61 | % | ALA3631113 | % | Homo sapiens | |||
8. | ALA3628627 | 4 | INH | = | 83.06 | % | ALA3631113 | % | Homo sapiens | |||
9. | ALA166031 | 3 | INH | = | 81.43 | % | ALA3631113 | % | Homo sapiens | |||
10. | ALA4872011 | 12 | INH | 0 | ALA4842525 | Active | % | Homo sapiens | ||||
11. | ALA4871408 | 11 | INH | 0 | ALA4842525 | Active | % | Homo sapiens | ||||
12. | ALA4872011 | 12 | INH | 0 | ALA4842522 | Dose-Dependent Effect | % | Homo sapiens | ||||
13. | ALA4871408 | 11 | INH | 0 | ALA4842522 | Dose-Dependent Effect | % | Homo sapiens | ||||
14. | ALA4872011 | 12 | INH | 0 | ALA4842519 | Active | % | Homo sapiens | ||||
15. | ALA4871408 | 11 | INH | 0 | ALA4842519 | Active | % | Homo sapiens | ||||
16. | SZM594 | 16 | Kd | = | 77 | nM | ALA4822734 | 7.11 | nM | Homo sapiens | ||
17. | TAK-632 | 8B, TAK-632 | Kd | = | 105 | nM | ALA4822734 | 6.98 | nM | Homo sapiens | ||
18. | ALA4850219 | (S)-SZM-777 | Kd | = | 145 | nM | ALA4822734 | 6.84 | nM | Homo sapiens | ||
19. | ALA4869920 | (R)-SZM-777 | Kd | = | 650 | nM | ALA4822734 | 6.19 | nM | Homo sapiens | ||
20. | ALA4860842 | SZM-777 | Kd | = | 270 | nM | ALA4822734 | 6.57 | nM | Homo sapiens |