# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Pyrimethamine | Pyrimethamine | IC50 | = | 139 | nM | ALA4423789 | 6.86 | nM | Toxoplasma gondii | ||
2. | ALA3953119 | 16; TRC-19 | IC50 | = | 8.76 | nM | ALA4423789 | 8.06 | nM | Toxoplasma gondii | ||
3. | Trimethoprim | 139 | IC50 | = | 33100 | nM | ALA4423789 | 4.48 | nM | Toxoplasma gondii | ||
4. | Methotrexate | 138 | IC50 | = | 78.3 | nM | ALA4423789 | 7.11 | nM | Toxoplasma gondii | ||
5. | trimetrexate | TMQ | IC50 | = | 1.35 | nM | ALA4423789 | 8.87 | nM | Toxoplasma gondii | ||
6. | ALA4553229 | 7 | IC50 | = | 209 | nM | ALA4423789 | 6.68 | nM | Toxoplasma gondii | ||
7. | ALA4544467 | 8 | IC50 | = | 30.9 | nM | ALA4423789 | 7.51 | nM | Toxoplasma gondii | ||
8. | ALA4552468 | 9 | IC50 | = | 31.5 | nM | ALA4423789 | 7.50 | nM | Toxoplasma gondii | ||
9. | ALA4569184 | 10 | IC50 | > | 10000 | nM | ALA4423789 | nM | Toxoplasma gondii | |||
10. | ALA4549054 | 11 | IC50 | = | 75.3 | nM | ALA4423789 | 7.12 | nM | Toxoplasma gondii | ||
11. | ALA4525462 | 12 | IC50 | = | 181 | nM | ALA4423789 | 6.74 | nM | Toxoplasma gondii | ||
12. | ALA4463544 | 13 | IC50 | > | 10000 | nM | ALA4423789 | nM | Toxoplasma gondii | |||
13. | ALA4544894 | 14 | IC50 | = | 39.8 | nM | ALA4423789 | 7.40 | nM | Toxoplasma gondii | ||
14. | ALA4456834 | 15 | IC50 | = | 45.9 | nM | ALA4423789 | 7.34 | nM | Toxoplasma gondii | ||
15. | ALA4546142 | 16 | IC50 | = | 57.8 | nM | ALA4423789 | 7.24 | nM | Toxoplasma gondii | ||
16. | ALA4535103 | 17 | IC50 | = | 62.1 | nM | ALA4423789 | 7.21 | nM | Toxoplasma gondii | ||
17. | ALA4439025 | 18 | IC50 | = | 12.9 | nM | ALA4423789 | 7.89 | nM | Toxoplasma gondii | ||
18. | ALA4435247 | 19 | IC50 | = | 29 | nM | ALA4423789 | 7.54 | nM | Toxoplasma gondii | ||
19. | ALA4459877 | 20 | IC50 | = | 9.19 | nM | ALA4423789 | 8.04 | nM | Toxoplasma gondii | ||
20. | ALA4582435 | 21 | IC50 | = | 3.91 | nM | ALA4423789 | 8.41 | nM | Toxoplasma gondii |