# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA526243 | TCMDC-137820 | IC50 | = | 6.4 | nM | ALA3739010 | 8.19 | nM | Lactobacillus casei | ||
2. | Dihydrofolic acid | H2F | Km | = | 3.6 | 10'-7M | ALA3283866 | nM | Lactobacillus casei | |||
3. | ALA3274194 | 7,8-Dihydropteroyl-D-glutamate | INH | = | 22 | % | ALA3283859 | % | Lactobacillus casei | |||
4. | ALA3274193 | dl-5,10-Methylene tetrahydropteroyl-D-glutamate | INH | = | 0 | % | ALA3283858 | % | Lactobacillus casei | |||
5. | ALA3274193 | dl-5,10-Methylene tetrahydropteroyl-D-glutamate | INH | = | 0 | % | ALA3283858 | % | Lactobacillus casei | |||
6. | ALA3274194 | 7,8-Dihydropteroyl-D-glutamate | deltaOD | = | 0.025 | /min | ALA3283857 | /min | Lactobacillus casei | |||
7. | ALA3274193 | dl-5,10-Methylene tetrahydropteroyl-D-glutamate | deltaOD | = | 0.032 | /min | ALA3283856 | /min | Lactobacillus casei | |||
8. | ALA3274193 | dl-5,10-Methylene tetrahydropteroyl-D-glutamate | deltaOD | = | 0.032 | /min | ALA3283856 | /min | Lactobacillus casei | |||
9. | Dihydrofolic acid | H2F | deltaOD | = | 0.032 | /min | ALA3283855 | /min | Lactobacillus casei | |||
10. | ALA3274194 | 7,8-Dihydropteroyl-D-glutamate | deltaOD | = | 0.015 | /min | ALA3283855 | /min | Lactobacillus casei | |||
11. | ALA3273854 | 15 | IC50 | = | 450 | 10'-8M | ALA3285765 | 5.35 | nM | Lactobacillus casei | ||
12. | ALA3273853 | 14 | IC50 | = | 360 | 10'-8M | ALA3285765 | 5.44 | nM | Lactobacillus casei | ||
13. | ALA3274179 | 8-Methyltetrahydromethotrexate | IC50 | = | 250 | 10'-8M | ALA3285765 | 5.60 | nM | Lactobacillus casei | ||
14. | ALA3273850 | 11 | IC50 | = | 180 | 10'-8M | ALA3285765 | 5.75 | nM | Lactobacillus casei | ||
15. | ALA3273848 | 9 | IC50 | = | 90 | 10'-8M | ALA3285765 | 6.05 | nM | Lactobacillus casei | ||
16. | ALA3273851 | 12 | IC50 | = | 87 | 10'-8M | ALA3285765 | 6.06 | nM | Lactobacillus casei | ||
17. | ALA3273852 | 13 | IC50 | = | 74 | 10'-8M | ALA3285765 | 6.13 | nM | Lactobacillus casei | ||
18. | ALA3273849 | 10 | IC50 | = | 38 | 10'-8M | ALA3285765 | 6.42 | nM | Lactobacillus casei | ||
19. | ALA3273855 | Tetrahydromethotrexate | IC50 | = | 20 | 10'-8M | ALA3285765 | 6.70 | nM | Lactobacillus casei | ||
20. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | IC50 | = | 14 | 10'-8M | ALA3285765 | 6.85 | nM | Lactobacillus casei |