# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2070497 | 18 | INH | = | 72 | % | ALA2071844 | % | Homo sapiens | |||
2. | N-[5-[6-(2,6-dichloro-4-methoxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]acetamide | 35 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
3. | ALA2070618 | 34 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
4. | ALA2070617 | 33 | IC50 | = | 2740 | nM | ALA2071843 | 5.56 | nM | Homo sapiens | ||
5. | ALA2070616 | 32 | IC50 | = | 612 | nM | ALA2071843 | 6.21 | nM | Homo sapiens | ||
6. | 1-ethyl-3-[5-[6-(4-methoxy-2,6-dimethylphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]urea | 31 | IC50 | = | 252 | nM | ALA2071843 | 6.60 | nM | Homo sapiens | ||
7. | ALA2070614 | 30 | IC50 | = | 415 | nM | ALA2071843 | 6.38 | nM | Homo sapiens | ||
8. | 1-[5-[6-(2,6-dimethyl-4-pentan-3-yloxyphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]-3-methylurea | 29 | IC50 | = | 415 | nM | ALA2071843 | 6.38 | nM | Homo sapiens | ||
9. | ALA2070612 | 28 | IC50 | > | 12500 | nM | ALA2071843 | nM | Homo sapiens | |||
10. | ALA2070611 | 27 | IC50 | = | 2013 | nM | ALA2071843 | 5.70 | nM | Homo sapiens | ||
11. | ALA2070505 | 26 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
12. | ALA2070504 | 25 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
13. | ALA2070503 | 24 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
14. | ALA2070502 | 23 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
15. | ALA2070501 | 22 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
16. | ALA2070500 | 21 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
17. | ALA2070499 | 20 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
18. | ALA2070498 | 19 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
19. | ALA2070496 | 17 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens | |||
20. | ALA2070495 | 16 | IC50 | > | 30000 | nM | ALA2071843 | nM | Homo sapiens |