| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2074599 | E3040 glucuronide | Ki | = | 5.6 | uM | ALA2077552 | 5.25 | inhibitor [Ki=5.6uM] | nM | Homo sapiens | |
| 2. |  ALA213947 | M2 | Ki | = | 337 | uM | ALA2077552 | inhibitor [Ki=337uM] | nM | Homo sapiens | ||
| 3. |  Glyburide | 2 | Activity | 0 | ALA2076990 | is not a inhibitor [-] | Homo sapiens | |||||
| 4. |  [³H]taurocholic acid | THCA | Activity | 0 | ALA2077551 | is not a substrate [-] | Homo sapiens | |||||
| 5. |  Glutathione (Reduced) | G33 | Activity | 0 | ALA2076877 | is not a substrate [-] | Homo sapiens | |||||
| 6. |  [³H]methotrexate | 138 | Ki | = | 1200 | uM | ALA2077552 | inhibitor [Ki=1200uM] | nM | Homo sapiens | ||
| 7. |  ALA493586 | 4-methylumbelliferone glucuronide | Ki | = | 105 | uM | ALA2077552 | inhibitor [Ki=105uM] | nM | Homo sapiens | ||
| 8. | [³H]taurocholic acid | THCA | IC50 | = | 40 | uM | ALA2076987 | 4.40 | inhibitor [IC50=40uM] | nM | Homo sapiens | |
| 9. |  ALA832 | Sulfinpyrazone | Activity | 0 | ALA2076991 | inhibitor [18 -> 83 % of control (clone#38), 30 -> 77 % of control (clone#77)] | Homo sapiens | |||||
| 10. |  Benzbromarone | 1 | Activity | 0 | ALA2076994 | inhibitor [18 -> 73 % of control (clone#38), 30 -> 67 % of control (clone#77)] | Homo sapiens | |||||
| 11. |  Indomethacin | Indomethacin | Activity | 0 | ALA2076993 | inhibitor [18 -> 67 % of control (clone#38), 30 -> 64 % of control (clone#77)] | Homo sapiens | |||||
| 12. |  Probenecid | probenecid | Activity | 0 | ALA2076992 | inhibitor [18 -> 59 % of control (clone#38), 30 -> 58 % of control (clone#77)] | Homo sapiens | |||||
| 13. | [³H]methotrexate | 138 | Km | = | 910 | uM | ALA2075317 | substrate [Km=910uM] | nM | Homo sapiens | ||
| 14. |  Ethynyl Estradiol 3-β-D-Glucuronide | 3-O-glucuronide of ethinylestradiol | Km | = | 9.2 | uM | ALA2076172 | substrate [Km=9.2uM] | nM | Homo sapiens | ||
| 15. | [³H]methotrexate | 138 | Km | = | 776 | uM | ALA2077089 | substrate [Km=776uM] | nM | Homo sapiens | ||
| 16. | [³H]methotrexate | 138 | Km | = | 620 | uM | ALA2076878 | substrate [Km=620uM] | nM | Homo sapiens | ||
| 17. | ALA213947 | M2 | Km | = | 5.7 | uM | ALA2077089 | substrate [Km=5.7uM] | nM | Homo sapiens | ||
| 18. |  ALA495936 | Leukotriene C4 (LTC4) | Km | = | 5.3 | uM | ALA2077089 | substrate [Km=5.3uM] | nM | Homo sapiens | ||
| 19. |  [³H]estradiol-17β-glucuronide | estradiol 17b glucuronide | Km | = | 42.9 | uM | ALA2077551 | substrate [Km=42.9uM] | nM | Homo sapiens | ||
| 20. | Indomethacin | Indomethacin | Activity | = | 1.8 | fold | ALA2076175 | inhibitor [1.8-fold increase of control] | fold | Homo sapiens |
The page will load shortly, Thanks for your patience!