# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MPP+ iodide | 1 | EC50 | = | 199 | uM | ALA5209618 | Substrate | nM | Homo sapiens | ||
2. | Ibrutinib (PCI-32765) | SID124898784 | IC50 | = | 7.9 | uM | ALA5209618 | 5.10 | Inhibitor | nM | Homo sapiens | |
3. | Nilotinib (AMN-107) | 38 | IC50 | = | 0.5 | uM | ALA5209618 | 6.30 | Inhibitor | nM | Homo sapiens | |
4. | (E)-1-Ethyl-2-((1-ethylquinolin-2(1H)-ylidene)methyl)quinolin-1-ium iodide | D22 | IC50 | = | 0.4 | uM | ALA5209618 | 6.40 | Inhibitor | nM | Homo sapiens | |
5. | Corticosterone | 7 | IC50 | = | 1.6 | uM | ALA5209618 | 5.80 | Inhibitor | nM | Homo sapiens | |
6. | ALA1617007 | DNDI1416976 | Drug uptake | 0 | ALA5119578 | Active | Homo sapiens | |||||
7. | Ethambutol | Ethambutol | Drug uptake | 0 | ALA5119578 | Active | Homo sapiens | |||||
8. | ALA3140030 | NMS | Drug uptake | 0 | ALA5119578 | Active | Homo sapiens | |||||
9. | Famotidine | Famotidine | Drug uptake | 0 | ALA5119578 | Active | Homo sapiens | |||||
10. | 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium | SID11111386 | Drug uptake | 0 | ALA5119578 | Active | Homo sapiens | |||||
11. | ALA1231492 | Benzyltriethyl-ammonium | INH | = | 49 | % | ALA5119575 | % | Homo sapiens | |||
12. | ALA1617007 | DNDI1416976 | INH | = | 58 | % | ALA5119575 | % | Homo sapiens | |||
13. | Ethambutol | Ethambutol | INH | = | -13 | % | ALA5119575 | % | Homo sapiens | |||
14. | Famotidine | Famotidine | INH | = | 29 | % | ALA5119575 | % | Homo sapiens | |||
15. | 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminium | SID11111386 | INH | = | 15 | % | ALA5119575 | % | Homo sapiens | |||
16. | ALA1617007 | DNDI1416976 | INH | = | 70 | % | ALA5119574 | % | Homo sapiens | |||
17. | Ethambutol | Ethambutol | INH | = | -7 | % | ALA5119574 | % | Homo sapiens | |||
18. | ALA3140030 | NMS | INH | = | 21 | % | ALA5119574 | % | Homo sapiens | |||
19. | Famotidine | Famotidine | INH | = | 56 | % | ALA5119574 | % | Homo sapiens | |||
20. | ALA1617007 | DNDI1416976 | INH | = | 63 | % | ALA5119573 | % | Homo sapiens |