# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | L-Thyroxine | 181 (Thyroxine) | IC50 | = | 8 | uM | ALA2075763 | 5.10 | inhibitor [IC50=8uM] | nM | Homo sapiens | |
2. | Digoxin | Digoxin | IC50 | 0 | ALA2075763 | inhibitor [80% of control (100, fitting IC50=540)uM] | Homo sapiens | |||||
3. | Digoxigenin | Digoxigenin | IC50 | = | 0.49 | uM | ALA2075764 | 6.31 | inhibitor [IC50=0.49uM] | nM | Homo sapiens | |
4. | Digitoxin | Digitoxin | IC50 | = | 0.12 | uM | ALA2075764 | 6.92 | inhibitor [IC50=0.12uM] | nM | Homo sapiens | |
5. | Digoxin | Digoxin | Km | = | 7.8 | uM | ALA2076885 | substrate [Km=7.8 +/- 2.0uM] | nM | Homo sapiens | ||
6. | 3,3',5-Triiodo-L-thyronine | 11 | Km | = | 5.9 | uM | ALA2076885 | substrate [Km=5.9 +/- 2.1uM] | nM | Homo sapiens | ||
7. | NSC 25485 | Ouabin | Km | = | 0.38 | uM | ALA2076885 | substrate [Km=0.38 +/- 0.1uM] | nM | Homo sapiens |