# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Benzbromarone | 1 | IC50 | = | 9 | uM | ALA2076210 | 5.05 | inhibitor [IC50=9u M] | nM | Rattus norvegicus | |
2. | ALA50 | quercetin | IC50 | = | 5 | uM | ALA2076210 | 5.30 | inhibitor [IC50=5u M] | nM | Rattus norvegicus | |
3. | α-Cyano-4-hydroxycinnamic Acid | 34 | IC50 | = | 24 | uM | ALA2076210 | 4.62 | inhibitor [IC50=24u M] | nM | Rattus norvegicus | |
4. | Phloretin | 19 ; phloretin | IC50 | = | 14 | uM | ALA2076210 | 4.85 | inhibitor [IC50=14u M] | nM | Rattus norvegicus | |
5. | D-Lactic Acid | d-Lactic acid | Km | = | 0.74 | mM | ALA2076210 | substrate [Km=0.74mM] | nM | Rattus norvegicus | ||
6. | DL-3-Hydroxybutyric Acid (contains Polymolecular esterification product) | 3-hydroxy butyrate | Ki | = | 1.2 | mM | ALA2076210 | inhibitor [Ki=1.2mM] | nM | Rattus norvegicus | ||
7. | ALA1230762 | Acetoacetate | Ki | = | 0.8 | mM | ALA2076210 | inhibitor [Ki=0.8mM] | nM | Rattus norvegicus | ||
8. | 3-Methyl-2-oxobutanoic acid | (Alpha-keto acid) ; table 2 | Ki | = | 0.3 | mM | ALA2076210 | inhibitor [Ki=0.3mM] | nM | Rattus norvegicus | ||
9. | ALA445647 | (Alpha-keto acid) ; table 2 | Ki | = | 0.1 | mM | ALA2076210 | 4.00 | inhibitor [Ki=0.1mM] | nM | Rattus norvegicus | |
10. | Pyruvic acid | 1 | Ki | = | 0.08 | mM | ALA2076210 | 4.10 | inhibitor [Ki=0.08mM] | nM | Rattus norvegicus | |
11. | Probenecid | probenecid | Activity | = | 88 | % | ALA2076210 | inhibitor [88% of control] | % | Rattus norvegicus | ||
12. | 4-Biphenylcarboxylic Acid | 1 | Activity | = | 74 | % | ALA2076210 | inhibitor [74% of control] | % | Rattus norvegicus | ||
13. | ALA1374360 | SID17389835 | Activity | = | 54 | % | ALA2076210 | inhibitor [54% of control] | % | Rattus norvegicus | ||
14. | Benzyl disulfide | NSC-677465 | Activity | = | 44 | % | ALA2076210 | inhibitor [44% of control] | % | Rattus norvegicus | ||
15. | α-Cyano-4-hydroxycinnamic Acid | 34 | Activity | = | 34 | % | ALA2076210 | inhibitor [34% of control] | % | Rattus norvegicus | ||
16. | Phloretin | 19 ; phloretin | Activity | = | 3 | % | ALA2076210 | inhibitor [3% of control] | % | Rattus norvegicus | ||
17. | NPPB | NCGC00024671-02 | Activity | = | 25 | % | ALA2076210 | inhibitor [25% of control] | % | Rattus norvegicus | ||
18. | ALA50 | quercetin | Activity | = | 17 | % | ALA2076210 | inhibitor [17% of control] | % | Rattus norvegicus | ||
19. | Niflumic acid | Niflumic acid | Activity | = | 14 | % | ALA2076210 | inhibitor [14% of control] | % | Rattus norvegicus | ||
20. | 5,8,11,14-Eicosatetraynoic acid | ETYA | Activity | = | 125 | % | ALA2076210 | inhibitor [125% of control] | % | Rattus norvegicus |