# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2074954 | Nalpha-sulfonated thyroxine | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
2. | Thyroxine 4′-O-Sulfate | 4'-OH-sulfonated thyroxine | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
3. | (S)-(-)-Tyrosine | 6 | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
4. | L-Tryptophan | 7 | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
5. | L-Leucine | Leucine | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
6. | L-Phenylalanine | phenylalanine | Activity | 0 | ALA2076811 | is not a substrate [-] | Rattus norvegicus | |||||
7. | L-Thyroxine | 181 (Thyroxine) | Km | = | 4.7 | uM | ALA2076811 | substrate [Km=4.7uM] | nM | Rattus norvegicus | ||
8. | 3,3′,5′-Triiodo-L-thyronine | reverse tri-iodothyronine (r-T3) | Km | = | 4 | uM | ALA2076811 | substrate [Km=4.0uM] | nM | Rattus norvegicus | ||
9. | ALA1312 | r-T3(4) | Km | = | 2.2 | uM | ALA2076811 | substrate [Km=2.2uM] | nM | Rattus norvegicus | ||
10. | ALA574431 | Sulfobromophthalein | Activity | = | 94 | % | ALA2075887 | inhibitor [94% of control] | % | Rattus norvegicus | ||
11. | ALA2074819 | N-bromoacetyl-3,3',5-triiodothyronine | Activity | = | 90 | % | ALA2075890 | inhibitor [90% of control] | % | Rattus norvegicus | ||
12. | D-Thyroxine | 12 | Activity | = | 76 | % | ALA2075893 | inhibitor [76% of control] | % | Rattus norvegicus | ||
13. | 3,3′,5-Triiodothyroacetic acid | 3 | Activity | = | 76 | % | ALA2075895 | inhibitor [76% of control] | % | Rattus norvegicus | ||
14. | L-Thyroxine | 181 (Thyroxine) | Activity | = | 69 | % | ALA2075891 | inhibitor [69% of control] | % | Rattus norvegicus | ||
15. | ALA2074819 | N-bromoacetyl-3,3',5-triiodothyronine | Activity | = | 67 | % | ALA2075899 | inhibitor [67% of control] | % | Rattus norvegicus | ||
16. | 3,3',5-Triiodo-L-thyronine | 11 | Activity | = | 57 | % | ALA2075901 | inhibitor [57% of control] | % | Rattus norvegicus | ||
17. | 3,3′,5-Triiodothyroacetic acid | 3 | Activity | = | 47 | % | ALA2075904 | inhibitor [47% of control] | % | Rattus norvegicus | ||
18. | (S)-(-)-Tyrosine | 6 | Activity | = | 37 | % | ALA2075888 | inhibitor [37% of control] | % | Rattus norvegicus | ||
19. | L-Thyroxine | 181 (Thyroxine) | Activity | = | 26 | % | ALA2075900 | inhibitor [26% of control] | % | Rattus norvegicus | ||
20. | 3,3′,5′-Triiodo-L-thyronine | reverse tri-iodothyronine (r-T3) | Activity | = | 24 | % | ALA2075903 | inhibitor [24% of control] | % | Rattus norvegicus |