# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5275820 | MNI-617 | Kd | = | 0.26 | nM | ALA5227538 | 9.59 | nM | Homo sapiens | ||
2. | (R)-(-)-Rolipram | (-)-Rolipram | Kd | = | 1.6 | nM | ALA5227538 | 8.80 | nM | Homo sapiens | ||
3. | Ibudilast | Ibudilast | IC50 | <= | 10 | uM | ALA5227533 | nM | Homo sapiens | |||
4. | ALA5269793 | 117 | IC50 | = | 0.001 | uM | ALA5226642 | 9.15 | nM | Homo sapiens | ||
5. | ALA364291 | table 2 Zardaverine (19) | IC50 | = | 0.8 | uM | ALA5226642 | 6.10 | nM | Homo sapiens | ||
6. | RO 20-1724 | Ro-201724 | IC50 | = | 2 | uM | ALA5226642 | 5.70 | nM | Homo sapiens | ||
7. | Theobromine | theobromine | IC50 | > | 100 | uM | ALA5223692 | nM | Homo sapiens | |||
8. | Theobromine | theobromine | Ki | > | 100 | uM | ALA5223687 | nM | Homo sapiens | |||
9. | GSK256066 | 4, GSK-256066 | IC50 | = | 3.2 | pM | ALA5152105 | nM | Homo sapiens | |||
10. | ALA1236215 | 1 | IC50 | = | 3.5 | uM | ALA5127008 | 5.46 | nM | Homo sapiens | ||
11. | Apremilast | 1S | IC50 | = | 0.11 | uM | ALA4397962 | 6.96 | nM | Homo sapiens | ||
12. | ALA4520636 | 2 | IC50 | = | 2.73 | uM | ALA4397905 | 5.56 | nM | Homo sapiens | ||
13. | ALA4536368 | 21 | IC50 | = | 2.58 | uM | ALA4397905 | 5.59 | nM | Homo sapiens | ||
14. | ALA4543264 | 20 | IC50 | = | 2.71 | uM | ALA4397905 | 5.57 | nM | Homo sapiens | ||
15. | ALA4443701 | 18 | IC50 | = | 2.16 | uM | ALA4397905 | 5.67 | nM | Homo sapiens | ||
16. | PDE4 inhibitor 16 | 16 | IC50 | = | 0.65 | uM | ALA4397905 | 6.19 | nM | Homo sapiens | ||
17. | ALA4592339 | 15 | IC50 | = | 5.83 | uM | ALA4397905 | 5.23 | nM | Homo sapiens | ||
18. | ALA4514693 | 14 | INH | = | 25.7 | % | ALA4397904 | % | Homo sapiens | |||
19. | ALA4450526 | 11 | INH | = | 36.7 | % | ALA4397904 | % | Homo sapiens | |||
20. | ALA4457093 | 19 | INH | = | 12.1 | % | ALA4397903 | % | Homo sapiens |