# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Ziprasidone | ziprasidone | Ki | = | 11 | nM | ALA3090824 | 7.96 | nM | Homo sapiens | ||
2. | [³H]prazosin | 1 | IC50 | = | 2 | 10'-10M | ALA2395712 | 9.70 | nM | Homo sapiens | ||
3. | [³H]prazosin | 1 | Ki | = | 5.4 | 10'-11M | ALA2395712 | 10.27 | nM | Homo sapiens | ||
4. | E1R | E1R, 4R,5S-2a | INH | = | -5 | % | ALA2393968 | % | Homo sapiens | |||
5. | E1R | E1R, 4R,5S-2a | INH | = | -5 | % | ALA2393965 | % | Homo sapiens | |||
6. | [³H]prazosin | 1 | IC50 | = | 0.17 | nM | ALA2395777 | 9.77 | nM | Homo sapiens | ||
7. | Atenolol | 3 | IC50 | = | 230 | nM | ALA2395775 | 6.64 | nM | Homo sapiens | ||
8. | ALA2392692 | 27, GSK2188931B | INH | < | 50 | % | ALA2395868 | % | Homo sapiens | |||
9. | ALA2386917 | 8 | Activity | 0 | ALA2387905 | Not Active | Homo sapiens | |||||
10. | ALA2322611 | 12a, (3S,4S)-12a | IC50 | = | 1 | uM | ALA2330852 | 6.00 | nM | Homo sapiens | ||
11. | ALA111612 | 10a | % inhibition | < | 10 | % | ALA4880240 | Not Active | % | Homo sapiens | ||
12. | ABT-100 | EUB0000289 | % inhibition | < | 10 | % | ALA4880161 | Not Active | % | Homo sapiens | ||
13. | ALA3697701 | BDBM161012 | % inhibition | 6 | % | ALA4880119 | Not Active | % | Homo sapiens | |||
14. | PF 04418948 | 15, PF-04418948 | % inhibition | 9 | % | ALA4886948 | Not Active | % | Homo sapiens | |||
15. | PF-04457845 | 23, PF-04457845 | % inhibition | -2 | % | ALA4883096 | Not Active | % | Homo sapiens | |||
16. | ABT 724 | 3a | % inhibition | 23 | % | ALA4880323 | Not Active | % | Homo sapiens | |||
17. | ALA3400586 | II | pKi | = | 7.05 | ALA3404316 | 7.05 | nM | Homo sapiens | |||
18. | ALA3400585 | I | pKi | = | 7.13 | ALA3404316 | 7.13 | nM | Homo sapiens | |||
19. | ALA3355137 | 17k | INH | = | 50 | % | ALA3387829 | % | Homo sapiens | |||
20. | ALA3343670 | 17 | Ki | > | 1000 | nM | ALA3381340 | nM | Homo sapiens |