# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Remibrutinib (LOU064) | 25; LOU064 | Activity | 0 | ALA4358630 | Not Active | Homo sapiens | |||||
2. | (S)-ARN2508 | (+)-10r | Activity | = | 1.2 | % | ALA3779487 | % | Homo sapiens | |||
3. | ALA3261926 | 10 | INH | = | 69 | % | ALA3268222 | % | Homo sapiens | |||
4. | ALA3261926 | 10 | IC50 | = | 2 | uM | ALA3268220 | 5.70 | nM | Homo sapiens | ||
5. | ALA242366 | 3b | IC50 | = | 4.7 | uM | ALA893371 | 5.33 | nM | Homo sapiens | ||
6. | ALA242367 | 4a | IC50 | = | 67 | uM | ALA893371 | 4.17 | nM | Homo sapiens | ||
7. | ALA390458 | 4b | IC50 | = | 8.6 | uM | ALA893371 | 5.07 | nM | Homo sapiens | ||
8. | ALA241945 | 5b | IC50 | = | 1.1 | uM | ALA893371 | 5.96 | nM | Homo sapiens | ||
9. | ALA241946 | 6b | IC50 | = | 0.66 | uM | ALA893371 | 6.18 | nM | Homo sapiens | ||
10. | ALA242157 | 7b | IC50 | = | 1.7 | uM | ALA893371 | 5.77 | nM | Homo sapiens | ||
11. | ALA390870 | 8b | IC50 | = | 1.9 | uM | ALA893371 | 5.72 | nM | Homo sapiens | ||
12. | ALA242369 | 9a | IC50 | = | 2.4 | uM | ALA893371 | 5.62 | nM | Homo sapiens | ||
13. | ALA242574 | 9b | IC50 | = | 1.2 | uM | ALA893371 | 5.92 | nM | Homo sapiens | ||
14. | Zileuton | A-64077 (Zileuton, 5) | IC50 | > | 100 | uM | ALA893371 | nM | Homo sapiens | |||
15. | ALA242365 | 3a | IC50 | = | 18 | uM | ALA893371 | 4.75 | nM | Homo sapiens | ||
16. | ALA244478 | 2b | IC50 | 0 | ALA893371 | Not Determined | Homo sapiens | |||||
17. | ALA242158 | 8a | IC50 | 0 | ALA893371 | Not Determined | Homo sapiens | |||||
18. | ALA244274 | 1b | IC50 | 0 | ALA893371 | Not Determined | Homo sapiens | |||||
19. | ALA371300 | 9 | Inhibition | = | 13.01 | % | ALA860352 | % | Homo sapiens | |||
20. | ALA371300 | 9 | Inhibition | = | 15.84 | % | ALA860351 | % | Homo sapiens |