# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Sildenafil | 1 | Ki | >= | 30 | nM | ALA5227555 | nM | Homo sapiens | |||
2. | TBA-7371 | 6 | IC50 | = | 4 | uM | ALA5139562 | 5.40 | nM | Homo sapiens | ||
3. | Tadalafil | 2 | IC50 | = | 5200 | nM | ALA5128072 | 5.28 | nM | Homo sapiens | ||
4. | Sildenafil | 1 | IC50 | = | 9.5 | nM | ALA5128072 | 8.02 | nM | Homo sapiens | ||
5. | ALA4062273 | 6c | IC50 | = | 30.1 | nM | ALA5121385 | 7.52 | nM | Homo sapiens | ||
6. | ALA2333219 | 7a | IC50 | = | 339 | nM | ALA5121385 | 6.47 | nM | Homo sapiens | ||
7. | ALA4554391 | 1; MT-3014 | IC50 | = | 0.561 | uM | ALA4349826 | 6.25 | nM | Homo sapiens | ||
8. | [(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]-(oxan-4-yl)methanone | 2q | IC50 | > | 50000 | nM | ALA4348841 | nM | Homo sapiens | |||
9. | ALA4575012 | 2p | IC50 | > | 20000 | nM | ALA4348841 | nM | Homo sapiens | |||
10. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348841 | nM | Homo sapiens | |||
11. | PF 04418948 | 15, PF-04418948 | % inhibition | 3 | % | ALA4887035 | Not Active | % | Homo sapiens | |||
12. | ALA4871796 | 26 | IC50 | = | 11 | uM | ALA4836297 | 4.96 | nM | Homo sapiens | ||
13. | ALA4873599 | 22 | IC50 | = | 27 | uM | ALA4836297 | 4.57 | nM | Homo sapiens | ||
14. | ALA4641729 | 8i | IC50 | = | 43.8 | uM | ALA4620084 | 4.36 | nM | Homo sapiens | ||
15. | ALA3092559 | 11 | IC50 | > | 10000 | nM | ALA3430110 | nM | Homo sapiens | |||
16. | ALA3331521 | 12 | IC50 | > | 10000 | nM | ALA3390278 | nM | Homo sapiens | |||
17. | ALA3356484 | 5d, MND | INH | 0 | ALA3381585 | Not Active | % | Homo sapiens | ||||
18. | AMG 579 | 5, AMG 579 | IC50 | > | 30 | uM | ALA3373748 | nM | Homo sapiens | |||
19. | ALA3291430 | 25 | IC50 | > | 100 | uM | ALA3291855 | nM | Homo sapiens | |||
20. | ALA3291427 | 22 | IC50 | = | 2 | uM | ALA3291855 | 5.70 | nM | Homo sapiens |