# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3359649 | Figure 9, R1C3 | IC50 | = | 1.11 | uM | ALA3383887 | 5.96 | nM | Homo sapiens | ||
2. | ALA2041596 | 13 | IC50 | = | 5.17 | uM | ALA3383887 | 5.29 | nM | Homo sapiens | ||
3. | ALA1927722 | 5 | IC50 | = | 1.04 | uM | ALA3383887 | 5.98 | nM | Homo sapiens | ||
4. | ALA3359633 | 42 | INH | 0 | ALA3383877 | Not Active | % | Homo sapiens | ||||
5. | ALA3359624 | 28 | INH | 0 | ALA3383877 | Not Active | % | Homo sapiens | ||||
6. | AMG 579 | 5, AMG 579 | IC50 | > | 30 | uM | ALA3373749 | nM | Homo sapiens | |||
7. | ALA4871796 | 26 | IC50 | > | 75 | uM | ALA4836298 | nM | Homo sapiens | |||
8. | ALA4873599 | 22 | IC50 | > | 75 | uM | ALA4836298 | nM | Homo sapiens | |||
9. | Tadalafil | 2 | IC50 | > | 10000 | nM | ALA4397442 | nM | Homo sapiens | |||
10. | Sildenafil | 1 | IC50 | > | 10000 | nM | ALA4397442 | nM | Homo sapiens | |||
11. | ALA4462192 | 15; TPN171 | IC50 | > | 10000 | nM | ALA4397442 | nM | Homo sapiens | |||
12. | [(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]-(oxan-4-yl)methanone | 2q | IC50 | > | 50000 | nM | ALA4348842 | nM | Homo sapiens | |||
13. | ALA4575012 | 2p | IC50 | > | 20000 | nM | ALA4348842 | nM | Homo sapiens | |||
14. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348842 | nM | Homo sapiens | |||
15. | ALA4589996 | 16 | IC50 | > | 10 | uM | ALA4339828 | nM | Homo sapiens | |||
16. | ALA4453464 | 1 | INH | < | 25 | % | ALA4339820 | % | Homo sapiens | |||
17. | ALA4542313 | 2 | INH | < | 25 | % | ALA4339820 | % | Homo sapiens | |||
18. | ALA5180503 | [11C]104; [11C]MICA-005 | IC50 | = | 1.7 | nM | ALA5227545 | 8.77 | nM | Homo sapiens | ||
19. | ALA5196667 | [18F]103; [18F]MICA-003 | IC50 | = | 17 | nM | ALA5227545 | 7.77 | nM | Homo sapiens | ||
20. | ALA3086091 | 26 | INH | = | 7 | uM | ALA3089586 | uM | Homo sapiens |