# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4246089 | 28h.HCl | pKi | = | 8.7 | ALA4375397 | 8.70 | nM | Homo sapiens | |||
2. | ALA4589933 | 16c; Diastereomeric mixture 4:1 | pIC50 | = | 5.4 | ALA4375392 | 5.40 | nM | Homo sapiens | |||
3. | ALA4239085 | 28u | pIC50 | = | 6.9 | ALA4375392 | 6.90 | nM | Homo sapiens | |||
4. | ALA4593110 | 16b; Diastereomeric mixture 3:1 | pIC50 | = | 5.8 | ALA4375392 | 5.80 | nM | Homo sapiens | |||
5. | ALA4446267 | 15b | pIC50 | = | 7.3 | ALA4375392 | 7.30 | nM | Homo sapiens | |||
6. | ALA4446786 | 16a; Diastereomeric mixture 5:1 | pIC50 | = | 6.1 | ALA4375392 | 6.10 | nM | Homo sapiens | |||
7. | ALA4238909 | 28c | pIC50 | = | 6.6 | ALA4375392 | 6.60 | nM | Homo sapiens | |||
8. | ALA4516070 | 14 | pIC50 | = | 5.3 | ALA4375392 | 5.30 | nM | Homo sapiens | |||
9. | ALA4573716 | 8 | pIC50 | = | 5.7 | ALA4375392 | 5.70 | nM | Homo sapiens | |||
10. | (3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S,3R)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate | 7 | pIC50 | = | 6.2 | ALA4375392 | 6.20 | nM | Homo sapiens | |||
11. | ALA4246089 | 28h.HCl | pIC50 | = | 7.3 | ALA4375392 | 7.30 | nM | Homo sapiens | |||
12. | ALA4448207 | 5 | pIC50 | = | 7 | ALA4375387 | 7.00 | nM | Homo sapiens | |||
13. | CWHM12 | 34, CWHM12 | IC50 | = | 1.8 | nM | ALA4375381 | 8.74 | nM | Homo sapiens | ||
14. | GLPG 0187 | 33, GLPG0187 | IC50 | = | 1.3 | nM | ALA4375385 | 8.89 | nM | Homo sapiens | ||
15. | ALA4800284 | 6j | pIC50 | = | 5.4 | ALA4709538 | 5.40 | nM | Homo sapiens | |||
16. | ALA4794201 | 19 | IC50 | < | 0.1 | nM | ALA4703086 | nM | Homo sapiens | |||
17. | ALA4741135 | 18 | IC50 | = | 0.3 | nM | ALA4703086 | 9.52 | nM | Homo sapiens | ||
18. | ALA4749110 | 17 | IC50 | < | 0.1 | nM | ALA4703086 | nM | Homo sapiens | |||
19. | ALA4756339 | 16 | IC50 | < | 0.1 | nM | ALA4703086 | nM | Homo sapiens | |||
20. | ALA4778229 | 15 | IC50 | = | 0.14 | nM | ALA4703086 | 9.85 | nM | Homo sapiens |
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