# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Vinblastine | Vinblastine | Activity | = | 50 | % | ALA2447121 | % | Sus scrofa | |||
2. | ALA2441610 | 13 | Activity | = | 41.2 | % | ALA2447121 | % | Sus scrofa | |||
3. | ALA1824506 | (R,S)-1.HCl | IC50 | = | 1.9 | uM | ALA2427438 | 5.72 | nM | Sus scrofa | ||
4. | ALA2425924 | 30.HCl | IC50 | = | 1.6 | uM | ALA2427438 | 5.80 | nM | Sus scrofa | ||
5. | Combretastatin A4 | CA-4 | IC50 | = | 1 | uM | ALA2427438 | 6.00 | nM | Sus scrofa | ||
6. | ALA1824506 | (R,S)-1.HCl | INH | = | 60 | % | ALA2427437 | % | Sus scrofa | |||
7. | ALA2425924 | 30.HCl | INH | = | 70 | % | ALA2427437 | % | Sus scrofa | |||
8. | Combretastatin A4 | CA-4 | INH | = | 80 | % | ALA2427437 | % | Sus scrofa | |||
9. | ALA1824506 | (R,S)-1.HCl | INH | = | 84 | uM | ALA2427436 | uM | Sus scrofa | |||
10. | ALA2425924 | 30.HCl | INH | = | 92 | % | ALA2427436 | % | Sus scrofa | |||
11. | Combretastatin A4 | CA-4 | INH | = | 99 | % | ALA2427436 | % | Sus scrofa | |||
12. | ALA2420525 | 6h | INH | 0 | ALA2422405 | Dose-dependent effect | % | Sus scrofa | ||||
13. | Vincristine | Vincristine | INH | 0 | ALA2422404 | Active | % | Sus scrofa | ||||
14. | Vinblastine | Vinblastine | INH | 0 | ALA2422404 | Active | % | Sus scrofa | ||||
15. | Tubulin Polymerization Inhibitor II | 7 | IC50 | = | 4.5 | uM | ALA2404660 | 5.35 | nM | Sus scrofa | ||
16. | ALA2402026 | 3 | IC50 | = | 16.4 | uM | ALA2404660 | 4.79 | nM | Sus scrofa | ||
17. | ALA2402027 | 4 | IC50 | > | 40 | uM | ALA2404660 | nM | Sus scrofa | |||
18. | ALA2402028 | 5 | IC50 | = | 19.14 | uM | ALA2404660 | 4.72 | nM | Sus scrofa | ||
19. | ALA2402029 | 6 | IC50 | > | 40 | uM | ALA2404660 | nM | Sus scrofa | |||
20. | ALA2402030 | 7 | IC50 | 0 | ALA2404660 | Not Determined | Sus scrofa |