# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756536 | 3a; BemPPOX | t1/2 | = | 0.52 | min | ALA4718668 | hr | Cavia porcellus | |||
2. | ALA458622 | 2 | t1/2 | = | 0.4 | min | ALA4718668 | hr | Cavia porcellus | |||
3. | ALA4756536 | 3a; BemPPOX | XI50 | = | 0.64 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
4. | ALA3402828 | ATM-114 | XI50 | > | 40 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
5. | ALA4747402 | 3c; BmPPOX | XI50 | > | 40 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
6. | ALA4752727 | 3d; iBmPPOX | XI50 | = | 0.52 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
7. | ALA4783307 | 3e; HmPPOX | XI50 | = | 1.09 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
8. | ALA4756951 | 3f; OmPPOX | XI50 | = | 1.47 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
9. | ALA4786753 | 3g; DmPPOX | XI50 | = | 2.72 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
10. | ALA4786177 | 3h; DomPPOX | XI50 | = | 1.17 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
11. | ALA4799246 | 3i; EhmPPOX | XI50 | = | 2.8 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
12. | ALA4793132 | 3j; MemPPOX | XI50 | = | 1.7 | molar excess | ALA4718656 | molar excess | Cavia porcellus | |||
13. | ALA4756536 | 3a; BemPPOX | INH | = | 62.1 | % | ALA4718655 | % | Cavia porcellus | |||
14. | ALA3402828 | ATM-114 | INH | = | 27.7 | % | ALA4718655 | % | Cavia porcellus | |||
15. | ALA4747402 | 3c; BmPPOX | INH | = | 43.8 | % | ALA4718655 | % | Cavia porcellus | |||
16. | ALA4752727 | 3d; iBmPPOX | INH | = | 76 | % | ALA4718655 | % | Cavia porcellus | |||
17. | ALA4783307 | 3e; HmPPOX | INH | = | 91.3 | % | ALA4718655 | % | Cavia porcellus | |||
18. | ALA4756951 | 3f; OmPPOX | INH | = | 63 | % | ALA4718655 | % | Cavia porcellus | |||
19. | ALA4786753 | 3g; DmPPOX | INH | = | 57.4 | % | ALA4718655 | % | Cavia porcellus | |||
20. | ALA4786177 | 3h; DomPPOX | INH | = | 54.4 | % | ALA4718655 | % | Cavia porcellus |