# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | (2E)-4-(dimethylamino)-1-[6-({5-methyl-4-[1-(propan-2-yl)-1H-pyrazol-4-yl]pyrimidin-2-yl}amino)-1,2,3,4-tetrahydroisoquinolin-2-yl]but-2-en-1-one | 13ac | INH | 0 | ALA4723877 | Not Active | % | Mus musculus | ||||
2. | ALA4536711 | D11 | Activity | 0 | ALA4339579 | Not Active | Mus musculus | |||||
3. | ALA2204366 | (R)-76 | INH | 0 | ALA2216406 | Active | % | Mus musculus | ||||
4. | ALA2204367 | (R)-84 | INH | 0 | ALA2216406 | Active | % | Mus musculus | ||||
5. | ALA2204367 | (R)-84 | INH | 0 | ALA2216403 | Active | % | Mus musculus | ||||
6. | ALA2204367 | (R)-84 | IC50 | = | 2.74 | uM | ALA2216405 | 5.56 | nM | Mus musculus | ||
7. | ALA2203687 | 7Z | INH | 0 | ALA2216403 | Not Active | % | Mus musculus | ||||
8. | ALA2204366 | (R)-76 | INH | 0 | ALA2216403 | Not Active | % | Mus musculus | ||||
9. | ALA2204367 | (R)-84 | INH | 0 | ALA2216402 | Active | % | Mus musculus | ||||
10. | ALA2204367 | (R)-84 | INH | 0 | ALA2216401 | Active | % | Mus musculus | ||||
11. | ALA2204367 | (R)-84 | INH | 0 | ALA2216404 | Active | % | Mus musculus | ||||
12. | ALA3109331 | 1 | INH | 0 | ALA3743647 | Not Active | % | Mus musculus | ||||
13. | ALA3740063 | 32 | INH | 0 | ALA3743647 | Active | % | Mus musculus | ||||
14. | ALA3740136 | 31 | INH | 0 | ALA3743647 | Active | % | Mus musculus | ||||
15. | ALA3741165 | 30 | INH | 0 | ALA3743647 | Active | % | Mus musculus | ||||
16. | ALA3741039 | 29 | INH | 0 | ALA3743647 | Active | % | Mus musculus | ||||
17. | ALA3739988 | 28 | INH | 0 | ALA3743647 | Active | % | Mus musculus |