# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Harmaline | 4 (Harmaline) | Ki | > | 10 | uM | ALA5235592 | nM | Homo sapiens | |||
2. | Harmalan | 6 | Ki | > | 10 | uM | ALA5235592 | nM | Homo sapiens | |||
3. | 6-Methoxyharmalan | 44 | Ki | > | 10 | uM | ALA5235592 | nM | Homo sapiens | |||
4. | ALA5274306 | 15 | INH | < | 50 | % | ALA5228811 | % | Homo sapiens | |||
5. | ALA5220371 | 12a | INH | < | 75 | % | ALA5217319 | % | Homo sapiens | |||
6. | ALA4777443 | EUB0000741a | Ki | = | 946 | nM | ALA5213917 | 6.02 | nM | Homo sapiens | ||
7. | ALA4539555 | EUB0000343 | % of inhibition | = | 47.69 | % | ALA5214377 | % | Homo sapiens | |||
8. | BAY 293 Negative Control | EUB0000743 | Ki | = | 1757.2 | nM | ALA5213938 | 5.75 | nM | Homo sapiens | ||
9. | ALA4594433 | ML-246 | Activity | < | 50 | % | ALA5168961 | % | Homo sapiens | |||
10. | RLX-33 | 33 | INH | < | 50 | % | ALA5167530 | % | Homo sapiens | |||
11. | ALA5200705 | 26 | Activity | = | 0.6 | % | ALA5164162 | % | Homo sapiens | |||
12. | ALA5200705 | 26 | Activity | = | -0.6 | % | ALA5164139 | % | Homo sapiens | |||
13. | ALA5207529 | 106 | Ki | = | 52.1 | nM | ALA5135869 | 7.28 | nM | Homo sapiens | ||
14. | ALA5204071 | 94 | Ki | = | 70.8 | nM | ALA5135869 | 7.15 | nM | Homo sapiens | ||
15. | ALA5170784 | 93 | Ki | = | 164 | nM | ALA5135869 | 6.79 | nM | Homo sapiens | ||
16. | ALA5182943 | 107 | INH | < | 50 | % | ALA5135868 | % | Homo sapiens | |||
17. | ALA5203937 | 19 | INH | 0 | ALA5129856 | NA | % | Homo sapiens | ||||
18. | 4-[[(2R)-2-hydroxy-2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl]amino]butyl 5-[[3-[(S)-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxycarbonylamino]-phenylmethyl]phenoxy]methyl]-1-methylpyrazole-3-carboxylate | 29 | INH | > | 65 | % | ALA5129856 | % | Homo sapiens | |||
19. | ALA5201712 | 37b | INH | 0 | ALA5129856 | NA | % | Homo sapiens | ||||
20. | EZM0414 | EZM-0414 | IC50 | = | 3.2 | uM | ALA5125562 | 5.50 | nM | Homo sapiens |