# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PF-4981517 | CYP3cide, PF-04981517 | INH | = | 53 | % | ALA3532541 | % | Homo sapiens | |||
2. | PF-4981517 | CYP3cide, PF-04981517 | INH | = | 47 | % | ALA3532540 | % | Homo sapiens | |||
3. | PF-4981517 | CYP3cide, PF-04981517 | IC50 | = | 1.4 | uM | ALA3532649 | 5.85 | nM | Homo sapiens | ||
4. | PF-4981517 | CYP3cide, PF-04981517 | IC50 | = | 0.33 | uM | ALA3532648 | 6.48 | nM | Homo sapiens | ||
5. | PF-4981517 | CYP3cide, PF-04981517 | IC50 | = | 0.16 | uM | ALA3532647 | 6.80 | nM | Homo sapiens | ||
6. | Cyclosporin A | 1a Cys-A | IC50 | = | 1.24 | uM | ALA3531037 | 5.91 | nM | Homo sapiens | ||
7. | Cyclosporin A | 1a Cys-A | IC50 | = | 1.47 | uM | ALA3531038 | 5.83 | nM | Homo sapiens | ||
8. | Cyclosporin A | 1a Cys-A | Ki | = | 0.98 | uM | ALA3531040 | 6.01 | nM | Homo sapiens | ||
9. | ALA269732 | FK-506 | IC50 | = | 0.94 | uM | ALA3531037 | 6.03 | nM | Homo sapiens | ||
10. | ALA269732 | FK-506 | IC50 | = | 0.74 | uM | ALA3531038 | 6.13 | nM | Homo sapiens | ||
11. | ALA269732 | FK-506 | Ki | = | 0.61 | uM | ALA3531040 | 6.21 | nM | Homo sapiens | ||
12. | ALA269732 | FK-506 | Ki | = | 0.36 | uM | ALA3541089 | 6.44 | nM | Homo sapiens | ||
13. | Cyclosporin A | 1a Cys-A | INH | 0 | ALA3531037 | Dose-dependent effect | % | Homo sapiens | ||||
14. | Cyclosporin A | 1a Cys-A | INH | 0 | ALA3531038 | Dose-dependent effect | % | Homo sapiens | ||||
15. | Hydralazine | Hydralazyne | Activity | = | 76 | % | ALA3532076 | % | Homo sapiens | |||
16. | Hydralazine | Hydralazyne | Activity | = | 98 | % | ALA3532075 | % | Homo sapiens | |||
17. | ALA3235164 | 19e | INH | 0 | ALA3243422 | Not Active | % | Homo sapiens | ||||
18. | ALA3235164 | 19e | INH | 0 | ALA3243419 | Not Active | % | Homo sapiens | ||||
19. | ALA3416047 | (+)-13h | INH | = | 27 | % | ALA3420145 | % | Homo sapiens | |||
20. | ALA3416051 | (+)-13j | INH | = | 27 | % | ALA3420145 | % | Homo sapiens |