# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | SIRT5 inhibitor 1 | 77 | Activity | > | 80 | % | ALA5141103 | % | Homo sapiens | |||
2. | ALA5188575 | 3b | Activity | > | 80 | % | ALA5141101 | % | Homo sapiens | |||
3. | ALA5183617 | 3i-he | IC50 | = | 9 | uM | ALA5141099 | 5.05 | nM | Homo sapiens | ||
4. | SIRT5 inhibitor 1 | 77 | IC50 | = | 10 | uM | ALA5141099 | 5.00 | nM | Homo sapiens | ||
5. | ALA5188575 | 3b | IC50 | = | 5 | uM | ALA5141099 | 5.30 | nM | Homo sapiens | ||
6. | ALA5187875 | 46; SBL 105 | IC50 | = | 86.01 | nM | ALA5128108 | 7.07 | nM | Homo sapiens | ||
7. | ALA582439 | 1 | IC50 | = | 1.1 | nM | ALA4386385 | 8.96 | nM | Homo sapiens | ||
8. | Mivebresib | BDBM220447 | INH | 0 | ALA4346395 | Active | % | Homo sapiens | ||||
9. | ALA4462804 | 27 | INH | 0 | ALA4346394 | Active | % | Homo sapiens | ||||
10. | ALA4521111 | 65 | IC50 | = | 66 | nM | ALA4346336 | 7.18 | nM | Homo sapiens | ||
11. | ALA4584480 | 64 | IC50 | = | 80 | nM | ALA4346336 | 7.10 | nM | Homo sapiens | ||
12. | ALA4555714 | 63 | IC50 | = | 6.2 | nM | ALA4346336 | 8.21 | nM | Homo sapiens | ||
13. | ALA4552305 | 62 | IC50 | = | 13 | nM | ALA4346336 | 7.89 | nM | Homo sapiens | ||
14. | ALA4452278 | 61 | IC50 | = | 10 | nM | ALA4346336 | 8.00 | nM | Homo sapiens | ||
15. | ALA4455214 | 60 | IC50 | = | 25 | nM | ALA4346336 | 7.60 | nM | Homo sapiens | ||
16. | ALA4442074 | 59 | IC50 | = | 14 | nM | ALA4346336 | 7.85 | nM | Homo sapiens | ||
17. | ALA4579396 | 58 | IC50 | = | 3100 | nM | ALA4346336 | 5.51 | nM | Homo sapiens | ||
18. | ALA4455576 | 57 | IC50 | = | 6.7 | nM | ALA4346336 | 8.17 | nM | Homo sapiens | ||
19. | ALA4587188 | 56 | IC50 | = | 24 | nM | ALA4346336 | 7.62 | nM | Homo sapiens | ||
20. | ALA4464739 | 55 | IC50 | = | 26 | nM | ALA4346336 | 7.58 | nM | Homo sapiens |